UniProt Accession

 NECP2_MOUSE; Q9D1J1; Q3U1M1; Q9CV41 

Genbank Protein ID

 BK000657; AK003463; AK009714; AK155871; BC037069 

Genbank Nucleotide ID

 DAA01434.1; BAB22803.1; BAB26458.1; BAE33474.1; AAH37069.1 

Protein Name

 Adaptin ear-binding coat-associated protein 2 

Protein Synonyms/Alias

 NECAP endocytosis-associated protein 2; NECAP-2 

Gene Name

 Necap2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
13	YESVLCVKPEVHVYR	acetylation	[1]
13	YESVLCVKPEVHVYR	ubiquitination	[2]
58	KGKVAYIKLEDRTSG	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Involved in endocytosis (By similarity). 

Sequence Annotation

 MOTIF 243 246 WXXF motif 1.
 MOTIF 263 266 WXXF motif 2.  

Keyword

 Cell membrane; Complete proteome; Cytoplasmic vesicle; Endocytosis; Membrane; Protein transport; Reference proteome; Repeat; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 266 AA 

Protein Sequence

Gene Ontology

 GO:0030125; C:clathrin vesicle coat; IDA:UniProtKB.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 

Interpro

 IPR012466; NECAP-1.
 IPR011993; PH_like_dom. 

Pfam

 PF07933; DUF1681 

SMART

  

PROSITE

  

PRINTS