CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015383
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cancer susceptibility candidate protein 1 
Protein Synonyms/Alias
 Lung adenoma susceptibility protein 1 
Gene Name
 Casc1 
Gene Synonyms/Alias
 Las1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
567KGLEFHLKGKWMAPIacetylation[1]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 730 AA 
Protein Sequence
MAPKSKKAPS KKKMTKAERL RLMQEEEERR LKEEEEARLK FEKEEQERLE IQRIEREKWN 60
LLEKKDLERR SQELEELALL EGCFPEAEKQ KREIRALAQW KHYTECDGSP DPWVAQEMNT 120
FISLWEEEKN QAFEQVMEKS KLVLSLIEKV KLILLETPTY ELDHRTVLQH QGSILRLQEL 180
LSLKINVATE LLLRQASNLA DLDTGNMEKI IKDENVTLYV WANLKKNPRH RSVRFSETQI 240
GFEIPRILAT SNVALRLLHT RYDHITPLFP IAVTEQNQNP VGAEQVNVEE STEKAMTEEK 300
LFTEEKAANE DEQPKAEQER ELNLVQEENK YEAIENTVLQ RTSDSEGEDS QTTQLELEMK 360
LLSEAVLAAQ LCLVENVVEL PEASQAYKVD LCHFSTLGGV YHLDVLELPP QCKPVKGWVL 420
VEILQEGLQR FIYPPDTTEE PDPDVTFPPI EVTLEIHKSV IFFERPRVVR WDNEGKFWRS 480
DGISSVYYNR EDRLLTFSMD TLGPVTLIQD AHVNMPYQSW EMSPCGMNKV LLIVKTVFME 540
LQIYIKENLC MLASVKLRGK GLEFHLKGKW MAPIPFILAL KEAGLNIFPA VYSHFYVVIN 600
NKVPQVELKA YRQMALLSSA FSFGWSKWNM VCNSTRVVIR VREQLSEETE HHTWSLLMFS 660
GDRAQMLKMQ EENDKFSEAL REGTEFHSTL YHMMKDFASP VAMERVRHSN CQFIDSVCYM 720
LLSIRVLSYS 730 
Gene Ontology
 GO:0005881; C:cytoplasmic microtubule; IDA:MGI.
 GO:0048487; F:beta-tubulin binding; IDA:MGI.
 GO:0008017; F:microtubule binding; IDA:MGI. 
Interpro
 IPR023247; Casc1.
 IPR022110; Casc1_domain. 
Pfam
 PF12366; Casc1 
SMART
  
PROSITE
  
PRINTS
 PR02043; CANCERSCCP1.