CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027336
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 6-phosphofructokinase, putative 
Protein Synonyms/Alias
  
Gene Name
 PFI0755c 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
928PEHSLFDKENRNKVCacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1418 AA 
Protein Sequence
MDTKSGDKNA ANKGGADGLV KTVSVLLRDN KCQFNIDENY DHNDKEKLEC EVGKRDSGMI 60
NCLMEKLTSK KFLEEKESKN SFYLVDNENM KIKKLKEHGH SASLNDDLSP LQYERTKYIP 120
SLPKALASEY QILDENYGDE FINKNDYEDV KRFLKNLHNL PMLNVKDSNN NESFKGGNIL 180
KIGIILSGGP APGGHNVISG IYDYAKRYNE QSQVIGFLGG IDGLYSKNYV TITDSMMNRF 240
RNLGGFNMLW SGRGKVKNKD DLIAIENIVA KLKLNGLVII GGDGSNSNAA LMAEYFAERQ 300
IPISIIGVPK TIDGDLKSEA IEISFGFDTA TRTYSEIIGN LCTDVKTGHN VYHVVRVMGR 360
SASHVVLECA LQTRPNVVLI GEEVEQLNLS LKDIVKNIVN IILKRKSLNK NYGVILLPEG 420
LIEFVPEMKI LISELNVILK DGPFDASKLQ KSKEVWDFLP PIIRDQLLMD RESTGYIQVG 480
KIATERLIIV LVESELAKLN DKNLNIQFMS HYLGYEGRCA IPSNFDCNYC YALGYNAALL 540
IDHKKTGYMS IIRNLEDSYT NWIPAAIPFL RIMHVIKDNT GNEFPAVKRY LVDLNSPLFN 600
VLKEVRSLWS LYDLYRSPGP IQFNGHLGNA RCYTVKTPTK DNLLCQNADD LELIINLTNK 660
NMYENNGDNN HNISDDKARD GGSSPTSSAK KTKYNLSDDN NNNNNNNINN VSTNYNNTSD 720
GSTFGNTTLL NTAYNVNGDG MNTLNCQKSN TSDVLSSEPV NQGFYEQHAS SYKSLGCMSE 780
LQTSRLYNKL ELPELCSDLK AKVRAGKQYI SNDPYTQKQI LSNYPHMSYE NKFQIQEIFH 840
DKYASPISFE IRIGIVFLSR QAPGAMNVLC GLYRRLKLLK GVCIAFYGLY GLLHNKYIII 900
DDDNIAKYVN QGGLELTGNS PEHSLFDKEN RNKVCETVTK LQLNGLVMPG SNITITEAAL 960
LSEYFLEKKI PTSVVGIPLT GSNNLIHELI ETCVGFDSST KVYASLIGNV LTDAVSMPKY 1020
WHFIRLMGRS PSHEVLECAL QTHPNVVIIS EEYGAADKTL WRVVQDIADV VCARADVGKN 1080
YGTVLIPDAL LMHLPHMKIL LSEISDILNE ASEKGQLLEA RNDLVNLSGV DHGHLTSEWV 1140
SKLTPWSLAL LKTFPQFIIK ELLQVDLRSM RFEQLETEQL LLQMVKEELQ DRKQKGKYSG 1200
SFMGLTHFFG YQGRSSLPSE FDCKLAYAYG HAASIVIESG LTGYIVSIRG LCGNVKDWKL 1260
FAIPFISLMK ILPKGQGSKY LKSASKGDLP VIPSAPVDLN GKAYRSLKIA LQKWQMEDRF 1320
CNPGPIQFEG NASNYYNRIL FEEQSEYFEM LRYVECYANI LKDTCRFGVS ADYLKNVFVQ 1380
LCGMLVLAYK PNDILSNMPY IGSIEDYYDW ENQRKRMN 1418 
Gene Ontology
 GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
 GO:0003872; F:6-phosphofructokinase activity; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0047334; F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity; IEA:InterPro.
 GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
 GO:0006096; P:glycolysis; IEA:InterPro. 
Interpro
 IPR011183; PfpB_PPi_PFK.
 IPR022953; Phosphofructokinase.
 IPR000023; Phosphofructokinase_dom.
 IPR001736; PLipase_D/transphosphatidylase.
 IPR013981; PPi-dep_PFK_a-hlx. 
Pfam
 PF00365; PFK 
SMART
  
PROSITE
 PS50035; PLD 
PRINTS
 PR00476; PHFRCTKINASE.