CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025728
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 LIM and SH3 protein 1, isoform CRA_b 
Protein Synonyms/Alias
 Lasp1 protein 
Gene Name
 Lasp1 
Gene Synonyms/Alias
 mCG_21894 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
17KIVYPTEKVNCLDKYubiquitination[1]
75TPENLRLKQQSELQSubiquitination[1]
96EFEKNKGKGFSVVADubiquitination[1]
128KYHEEFEKSRMGPSGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 LIM domain; Metal-binding; SH3 domain; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 263 AA 
Protein Sequence
MNPNCARCGK IVYPTEKVNC LDKYWHKACF HCETCKMTLN MKNYKGYEKK PYCNAHYPKQ 60
SFTMVADTPE NLRLKQQSEL QSQVRYKEEF EKNKGKGFSV VADTPELQRI KKTQDQISNI 120
KYHEEFEKSR MGPSGGEGVE PERREAQDSS SYRRPTEQQQ PQPHHIPTSA PVYQQPQQQQ 180
MTSSYGGYKE PAAPVSIQRS APGGGGKRYR AVYDYSAADE DEVSFQDGDT IVNVQQIDDG 240
WMYGTVERTG DTGMLPANYV EAI 263 
Gene Ontology
 GO:0030864; C:cortical actin cytoskeleton; IEA:Compara.
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005925; C:focal adhesion; IDA:MGI.
 GO:0051015; F:actin filament binding; IDA:MGI.
 GO:0015075; F:ion transmembrane transporter activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR000900; Nebulin_35r-motif.
 IPR001452; SH3_domain.
 IPR001781; Znf_LIM. 
Pfam
 PF00412; LIM
 PF00880; Nebulin
 PF00018; SH3_1 
SMART
 SM00132; LIM
 SM00227; NEBU
 SM00326; SH3 
PROSITE
 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2
 PS51216; NEBULIN
 PS50002; SH3 
PRINTS
 PR00452; SH3DOMAIN.