CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038277
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Scaf11 
Protein Synonyms/Alias
  
Gene Name
 Scaf11 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1169ASSWAVRKTLPADVQacetylation[1]
1169ASSWAVRKTLPADVQubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1456 AA 
Protein Sequence
MKKKSVYNQN VGDQECDDME GEENSNTADA SGLLYSEADR CPICLSCLLG KEVGFPESCN 60
HVFCMACILK WAEILASCPI DRKPFQAVFE LSAFEGCAKI QVKRRLRETE DKENQRSFKK 120
QLFYHESSKG NKRKRNTIRE DLLCERSDGL KVLYRNISNK MDGKKNATVK TNKVQRSNQC 180
TDSCIRNEMS SVFSCGSHSW GPRTHRASCT ESIEVNEISA LIRQKRQELE LSWFPNTLPG 240
NGRVGSVPWS VETAFLSLAS SGLPRTVFPA STTSLEHFGT SHKGYALAHT QGGGEKKQTS 300
GTSNTRGSRR KPAATAPTRR STRNTRAETV SQSQKSPVSN YSECDAPGNS NSSVSISPPA 360
ESEKQTRQAP KRKSVRRGRK PPLLKKKLRR SVPPAEKSSS DSVEEETVDS DTPPVLEKEQ 420
QSCVESSSIC SVQTDEENHL HLESCSEQTE ENEQANNHEI EEQTESLNSE SCTQDPPGLV 480
GEDTGIEAKE FCADHDISPD TSLRGRDSAE HQEQLSGSSE SEVQALVCTE SPPEGSPTCP 540
PSDIEHQPVS SPLGEVSDNT TPVVSDERAE ESLTVESTDL NDERTGESLT VESTDLNDSA 600
VNIEAFVESP KMESCEGETA QGLDRHCVPS SDSELPEHIQ TENTEIIPAC EHIQTENTEI 660
IPACEHIQTE NTEIIPVCGT LENENSDAVQ DCEDNLLKHN LDNSQSDKFL EETTESLVEH 720
PIHAELPHKE VDQSEKHFSE DNNESVPMEC DSFCSDQNES EVESSANTDS KQLSENSVPH 780
SSEDKLSSDP AVEKVETVAQ PAESLVDKAP KPRTRRSRFH SPSTTWSPNK DAAQEKRRAQ 840
SPSPKRETVV ESQSSQSPSP KRESARGRRK SRSLSPKKDV ARERRQSRSP KRENAREAKR 900
SESGSPRRDT SRENQRSQSR VKDSSSREKS RSRSRERESD REAQRRERDR ERRARRWSRS 960
RSRSRSPSRL RTKSKSSSFG RNERDNYSPR WKERWTNDGW RCPRGNDRYR RNDSEKQNEN 1020
TRNEKNDITA DSNDPSSTDK HRSDCPSWVT EKINSGPDPR TRNPEKLKDS HWEENRNENS 1080
GNSWTKNFGP GWMSSRGRGG RGKGAYRGNF ACNDQSENRW QSRTPLSGSD SFKSAEQQPS 1140
KRKSEQELSF GTAADRSGWT SASSWAVRKT LPADVQSYYS RRGRNSSGPQ SGWMRQEEET 1200
PEQDSNLKDQ TNQVDGSQLP VNMMQPHMSV MQPPVNAPHP PVGVFPYPVG LPAPMMNMQR 1260
NPFTMHPPMP LHLHTGVPLM QVAAPASIPQ GPPPPPPPPP SQQVSYVASQ PDGKQVQGLS 1320
SASHVSNNMN TQVLPAPSAA PANTGSVQGP SSGNTSSSSH VQASNAAVKL AESKKLQIQE 1380
KAAQEVKLAI KPFYQNKDIT KEEYKEIVRK AVDKVCHSKS GEVNSTKVAN LVKAYVDKYR 1440
YSRKKALEEP GSTEKT 1456 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0000245; P:spliceosomal complex assembly; IEA:Compara. 
Interpro
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF13639; zf-RING_2 
SMART
 SM00184; RING 
PROSITE
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS