CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030646
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nuclear transition protein 2 
Protein Synonyms/Alias
  
Gene Name
 Tnp2 
Gene Synonyms/Alias
 rCG_49757 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
88NRKTLEGKVSKRKAVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins (By similarity). 
Sequence Annotation
  
Keyword
 Chromosome; Complete proteome; Developmental protein; Differentiation; DNA-binding; Metal-binding; Nucleosome core; Nucleus; Reference proteome; Spermatogenesis; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 114 AA 
Protein Sequence
MDTKMQSLPT THPHPHSSSR PQSHTNNQCA CSHHCRSCSQ AGHPSSSSSP SSGPPTKHPK 60
TPMHSRYSPS RPSHRGSCPK NRKTLEGKVS KRKAVRRRKR THRAKRRSSG RRYK 114 
Gene Ontology
 GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0007340; P:acrosome reaction; IEA:Compara.
 GO:0007339; P:binding of sperm to zona pellucida; IEA:Compara.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0007341; P:penetration of zona pellucida; IEA:Compara.
 GO:0030317; P:sperm motility; IEA:Compara.
 GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. 
Interpro
 IPR000678; TP2. 
Pfam
 PF01254; TP2 
SMART
  
PROSITE
 PS00970; TP2_1
 PS00971; TP2_2 
PRINTS