CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030855
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ61268, highly similar to Peroxisomal multifunctional enzyme type 2 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
594QKLQMILKDYAKL**ubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 599 AA 
Protein Sequence
MKKQKYGRIL MTSSASGIYG NFGQANYSAA KLGLLGLANS LAIEGRKSNI HCNTIAPNAG 60
SRMTQTVMPE DLVEALKPEY VAPLVLWLCH ESCEENGGLF EVGAGWIGKL RWERTLGAIV 120
RQKNHPMTPE AVKANWKKIC DFENASKPQS IQESTGSIIE VLSKIDSEGG VSANHTSRAT 180
STATSGFAGA IGQKLPPFSY AYTELEAIMY ALGVGASIKD PKDLKFIYEG SSDFSCLPTF 240
GVIIGQKSMM GGGLAEIPGL SINFAKVLHG EQYLELYKPL PRAGKLKCEA VVADVLDKGS 300
GVVIIMDVYS YSEKELICHN QFSLFLVGSG GFGGKRTSDK VKVAVAIPNR PPDAVLTDTT 360
SLNQAALYRL SGDWNPLHID PNFASLAGFD KPILHGLCTF GFSARRVLQQ FADNDVSRFK 420
AIKARFAKPV YPGQTLQTEM WKEGNRIHFQ TKVQETGDIV ISNAYVDLAP TSGTSAKTPS 480
EGGKLQSTFV FEEIGRRLKD IGPEVVKKVN AVFEWHITKG GNIGAKWTID LKSGSGKVYQ 540
GPAKGAADTT IILSDEDFME VVLGKLDPQK AFFSGRLKAR GNIMLSQKLQ MILKDYAKL 599 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0032934; F:sterol binding; IEA:InterPro.
 GO:0055114; P:oxidation-reduction process; IEA:GOC. 
Interpro
 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR002539; MaoC_dom.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS.
 IPR003033; SCP2_sterol-bd_dom. 
Pfam
 PF00106; adh_short
 PF01575; MaoC_dehydratas
 PF02036; SCP2 
SMART
  
PROSITE
 PS00061; ADH_SHORT 
PRINTS
 PR00081; GDHRDH.