CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038685
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein enabled homolog 
Protein Synonyms/Alias
  
Gene Name
 Enah 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
69CAIPKGLKYNQATQTubiquitination[1]
772RKELAKLKEELIDAIacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 789 AA 
Protein Sequence
MSEQSICQAR AAVMVYDDAN KKWVPAGGST GFSRVHIYHH TGNNTFRVVG RKIQDHQVVI 60
NCAIPKGLKY NQATQTFHQW RDARQVYGLN FGSKEDANVF ASAMMHALEV LNSQEAVFYL 120
GPTLPRQNSQ LPAQVQNGPS QEELEIQRRQ LQEQQRQKEL ERERMERERL ERERLERERL 180
ERERLEQEQL ERQRQEREHV ERLERERLER LERERQERER ERLEQLEREQ VEWERERRMS 240
NAAPSSDSSL SSAPLPEYSS CQPPSAPPPS YAKVISAPVS DATPDYAVVT ALPPTSTPPT 300
PPLRHAATRF ATSLGSAFHP VLPHYATVPR PLNKNSRPSS PVNTPSSQPP AAKSCAWPTS 360
NFSPLPPSPP IMISSPPGKA TGPRPVLPVC VSSPVPQMPP SPTAPNGSLD SVTYPVSPPP 420
TSGPAAPPPP PPPPPPPPPP PPPLPPPPLP PLASLSHCGS QASPPPGTPL ASTPSSKPSV 480
LPSPSAAAPA SAETPLNPEL GDSSASEPGL QAASQPAESP TPQGLVLGPP APPPPPPLPS 540
GPAYASALPP PPGPPPPPPL PSTGPPPPPP PPPPLPNQAP PPPPPPPAPP LPASGIFSGS 600
TSEDNRPLTG LAAAIAGAKL RKVSRVEDGS FPGGGNTGSV SLASSKADAG RGNGPLPLGG 660
SGLMEEMSAL LARRRRIAEK GSTIETEQKE DRNEDAEPIT AKAPSTSTPE PTRKPWERTN 720
TMNGSKSPVI SRPKSTPSSQ PSANGVQTEG LDYDRLKQDI LDEMRKELAK LKEELIDAIR 780
QELSKSNTA 789 
Gene Ontology
 GO:0030175; C:filopodium; IDA:MGI.
 GO:0030027; C:lamellipodium; IDA:MGI.
 GO:0001725; C:stress fiber; IDA:MGI.
 GO:0017124; F:SH3 domain binding; IDA:MGI.
 GO:0008154; P:actin polymerization or depolymerization; IDA:MGI.
 GO:0007411; P:axon guidance; IMP:MGI.
 GO:0046907; P:intracellular transport; IEA:InterPro.
 GO:0001843; P:neural tube closure; IGI:MGI. 
Interpro
 IPR000697; EVH1.
 IPR011993; PH_like_dom.
 IPR000156; Ran_bind_dom.
 IPR014885; VASP_tetra. 
Pfam
 PF08776; VASP_tetra
 PF00568; WH1 
SMART
 SM00160; RanBD
 SM00461; WH1 
PROSITE
 PS50229; WH1 
PRINTS