UniProt Accession

 HA10_MOUSE; P01898; O19475; Q31214; Q95HC3 

Genbank Protein ID

 K01207; K01205; X16426; AK131620; BC011215; M12484; K00614; X16206 

Genbank Nucleotide ID

 AAA39574.1; AAA39574.1; CAA34449.1; BAE20725.1; AAH11215.1; AAA39676.1; AAA39681.1; CAA34326.1 

Protein Name

 H-2 class I histocompatibility antigen, Q10 alpha chain 

Protein Synonyms/Alias

  

Gene Name

 H2-Q10 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
92	ERETQRAKGNEQSFH	ubiquitination	[1]
170	AAIITRRKWEQAGAA	ubiquitination	[1]
200	LRYLELGKETLLRTD	ubiquitination	[1]
210	LLRTDPPKTHVTHHP	ubiquitination	[1]
267	AGDGTFQKWASVVVP	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Involved in the presentation of foreign antigens to the immune system. 

Sequence Annotation

 DOMAIN 209 297 Ig-like C1-type.
 REGION 25 114 Alpha-1.
 REGION 115 206 Alpha-2.
 REGION 207 298 Alpha-3.
 REGION 299 310 Connecting peptide.
 CARBOHYD 110 110 N-linked (GlcNAc...).
 CARBOHYD 280 280 N-linked (GlcNAc...).
 DISULFID 125 188 By similarity.
 DISULFID 227 283 By similarity.  

Keyword

 Complete proteome; Disulfide bond; Glycoprotein; Immunity; Membrane; MHC I; Reference proteome; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 325 AA 

Protein Sequence

Gene Ontology

 GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; TAS:Reactome.
 GO:0042612; C:MHC class I protein complex; IEA:UniProtKB-KW.
 GO:0030670; C:phagocytic vesicle membrane; TAS:Reactome.
 GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:UniProtKB-KW.
 GO:0006955; P:immune response; IEA:InterPro. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR011161; MHC_I-like_Ag-recog.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR001039; MHC_I_a_a1/a2. 

Pfam

 PF07654; C1-set
 PF00129; MHC_I 

SMART

 SM00407; IGc1 

PROSITE

 PS50835; IG_LIKE
 PS00290; IG_MHC 

PRINTS

 PR01638; MHCCLASSI.