CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014463
UniProt Accession
Genbank Protein ID
 U34932 
Genbank Nucleotide ID
Protein Name
 Rab GTPase-binding effector protein 2 
Protein Synonyms/Alias
 MP13 protein; Rabaptin-5beta 
Gene Name
 Rabep2 
Gene Synonyms/Alias
 Rabpt5b 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
92ETQIAALKQERQQQQubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
 Plays a role in membrane trafficking and in homotypic early endosome fusion (By similarity). 
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Cytoplasm; Endocytosis; Endosome; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 554 AA 
Protein Sequence
MAAAPAALAL DPQPQEEQKD ASESSELSRL RAELAGALAE METMKAVAEV SESTKAEAVA 60
AVQRQCQEEV ASLQAILKDS ISSYETQIAA LKQERQQQQQ DSEEKERELG HLKQLLARAH 120
PLDSLEKQME KAHEDSEKLR EIVLPMEQEI AELKVKLLRA EELIQEIQRR PRQPASLHGS 180
TELLPLSRNP SPPLEPSEEP SGDAGPAAEA FAHNCDDSAS ISSFSLGGAA GSVSLRGPQG 240
LSPEQEETAS LVSTGTLVPE GIYLPPPGYQ LVPDSQWEQL QVEGRQLQKE LESVRRERDE 300
LQEGLSRSNE DCAKQMQVLL AQVQNSEQLL RTLQGTVSQA QERVQRQMAE LATSHKCLSQ 360
EVKRLNEENR GLRAEQLPSS ALQGSEQQED QDEALPSSIQ ELHQLVRHTR QQARARQQAQ 420
EHEAERLRIE IVKLREALDE ETAAKASLEG QLRVQREETD VLEASLCSLR IETERVQQEH 480
HKAQLTDLLS EQRAKALRLQ AELETSEQVQ RDFVRLSQAL QVRLEQIRQA DTLEQVRSIL 540
DEAPLRDIKD IKDS 554 
Gene Ontology
 GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
 GO:0005096; F:GTPase activator activity; IEA:InterPro.
 GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
 GO:0043547; P:positive regulation of GTPase activity; IEA:GOC.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR003914; Rabaptin.
 IPR018514; Rabaptin_coiled-coil.
 IPR015390; Rabaptin_Rab5-bd_dom. 
Pfam
 PF09311; Rab5-bind
 PF03528; Rabaptin 
SMART
  
PROSITE
  
PRINTS
 PR01432; RABAPTIN.