CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037936
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 ATP-dependent RNA helicase DDX25 
Protein Synonyms/Alias
  
Gene Name
 DDX25 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
31HRVEVLQKDPSSPLYubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 407 AA 
Protein Sequence
XLVDLAANSL LNKLIHQSLV ESSHRVEVLQ KDPSSPLYSV KTFEELRLKE ELLKGIYAMG 60
FNRPSKIQEM ALPMMLAHPP QNLIAQSQSG TGKTAAFVLA MLSRVNALEL FPQCLCLAPT 120
YELALQTGRV VEQMGKFCVD VQVMYAIRGN RNWCFKLKLI DLTKIRVFVL DEADVMIDTQ 180
GFSDHSIRIQ RALPSECQML LFSATFEDSV WHFAERIIPD PNVIKLRKEE LTLNNIRQYY 240
VLCEHRKDKY QALCNIYGSI TIGQAIIFCQ TRRNAKWLTV EMIQDGHQVS LLSGELTVEQ 300
RASIIQRFRD GKEKVLITTN VCARGIDVKQ VTIVVNFDLP VKQGEEPDYE TYLHRIGRTG 360
RFGKKGLAFN MIEVDELPSL MKIQDHFNSS IKQLNAEDMD EIEKIDY 407 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR014014; RNA_helicase_DEAD_Q_motif. 
Pfam
 PF00270; DEAD
 PF00271; Helicase_C 
SMART
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER
 PS51195; Q_MOTIF 
PRINTS