UniProt Accession

 E9Q327_MOUSE; E9Q327 

Genbank Protein ID

 AC149282 

Genbank Nucleotide ID

  

Protein Name

 Apolipoprotein E 

Protein Synonyms/Alias

  

Gene Name

 Apoe 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
86	TEVKAYKKELEEQLG	ubiquitination	[1]
105	ETRARLGKEVQAAQA	ubiquitination	[1]
173	QKRLAVYKAGAREGA	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Lipid transport; Reference proteome; Secreted; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 221 AA 

Protein Sequence

Gene Ontology

 GO:0005615; C:extracellular space; IDA:MGI.
 GO:0017127; F:cholesterol transporter activity; IDA:MGI.
 GO:0008289; F:lipid binding; IEA:InterPro.
 GO:0071813; F:lipoprotein particle binding; IDA:MGI.
 GO:0048844; P:artery morphogenesis; IGI:MGI.
 GO:0006874; P:cellular calcium ion homeostasis; IDA:MGI.
 GO:0006707; P:cholesterol catabolic process; IMP:MGI.
 GO:0033344; P:cholesterol efflux; IDA:MGI.
 GO:0042632; P:cholesterol homeostasis; IMP:MGI.
 GO:0042158; P:lipoprotein biosynthetic process; IGI:MGI.
 GO:0042159; P:lipoprotein catabolic process; IMP:MGI.
 GO:0051651; P:maintenance of location in cell; IMP:MGI.
 GO:0010468; P:regulation of gene expression; IMP:MGI.
 GO:0002021; P:response to dietary excess; IMP:MGI.
 GO:0006979; P:response to oxidative stress; IMP:MGI.
 GO:0042311; P:vasodilation; IMP:MGI. 

Interpro

 IPR013326; ApoA.
 IPR000074; ApoA1_A4_E. 

Pfam

 PF01442; Apolipoprotein 

SMART

  

PROSITE

  

PRINTS