UniProt Accession

 A2ABE9_HUMAN; A2ABE9 

Genbank Protein ID

 AL662899; CR759787 

Genbank Nucleotide ID

  

Protein Name

 MutS protein homolog 5 

Protein Synonyms/Alias

  

Gene Name

 MSH5 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
25	RALGGLLKFLGRRRI	ubiquitination	[1]
50	VPILGFKKFMLTHLV	ubiquitination	[1]
86	YKVASGLKEGLSLFG	ubiquitination	[1]
248	IDPEIDEKKRRLMGL	ubiquitination	[2]
249	DPEIDEKKRRLMGLP	ubiquitination	[1]
265	FLTEVARKELENLDS	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 333 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0030983; F:mismatched DNA binding; IEA:InterPro.
 GO:0006298; P:mismatch repair; IEA:InterPro. 

Interpro

 IPR007861; DNA_mismatch_repair_MutS_clamp.
 IPR007696; DNA_mismatch_repair_MutS_core. 

Pfam

 PF05192; MutS_III
 PF05190; MutS_IV 

SMART

 SM00533; MUTSd 

PROSITE

  

PRINTS