CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028339
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Bleomycin hydrolase 
Protein Synonyms/Alias
  
Gene Name
 Blmh 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
88VMRLPFMKKFNIEEFacetylation[1]
279NDPRPQHKYNKLYTVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 ACT_SITE 73 73 By similarity.
 ACT_SITE 372 372 By similarity.
 ACT_SITE 396 396 By similarity.  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 455 AA 
Protein Sequence
MNNAGLNSEK VAALIQKLNS DPQFVLAQNV GTTHDLLDIC LKRATVQGAQ HVFQHVVPQE 60
GKPVTNQKSS GRCWIFSCLN VMRLPFMKKF NIEEFEFSQS YLFFWDKVER CYFFLNAFVD 120
TAQKKEPEDG RLVQYLLMNP TNDGGQWDML VNIVEKYGVV PKKCFPESHT TEATRRMNDI 180
LNHKMREFCI RLRNLVHSGA TKGEISSTQD AMMEEIFRVV CICLGNPPET FTWEYRDKDK 240
NYHKVGPITP LQFYKEHVKP LFNMEDKICF VNDPRPQHKY NKLYTVDYLS NMVGGRKTLY 300
NNQPIDFLKK MVAASIRDGE AVWFGCDVGK HFNGKLGLSD MNVYDHELVF GVSLKNMNKA 360
ERLAFGESLM THAMTFTAVS EKDDQEGAFV KWRVENSWGE DHGHKGYLCM TDEWFSEYVY 420
EVVVDKKHVP EEVLAVLEQE PIVLPAWDPM GALAE 455 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0009636; P:response to toxic substance; IEA:Compara. 
Interpro
 IPR000169; Pept_cys_AS.
 IPR004134; Peptidase_C1B. 
Pfam
 PF03051; Peptidase_C1_2 
SMART
  
PROSITE
 PS00139; THIOL_PROTEASE_CYS 
PRINTS