CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-036914
UniProt Accession
E7EPM2_HUMAN
;
E7EPM2
Genbank Protein ID
AC011476
Genbank Nucleotide ID
Protein Name
NACHT, LRR and PYD domains-containing protein 7
Protein Synonyms/Alias
Gene Name
NLRP7
Gene Synonyms/Alias
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
560
LANEKRA
K
ELEATFG
ubiquitination
[1]
845
YKTMTRP
K
HFLQMLS
ubiquitination
[1]
Reference
[1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
Mol Cell. 2011 Oct 21;44(2):325-40. [
PMID: 21906983
]
Functional Description
Sequence Annotation
Keyword
ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
1065 AA
Protein Sequence
MSRKHRLEAR PDLREFFSLN LRSHTRSTMT SPQLEWTLQT LLEQLNEDEL KSFKSLLWAF 60
PLEDVLQKTP WSEVEEADGK KLAEILVNTS SENWIRNATV NILEEMNLTE LCKMAKAEMM 120
EDGQVQEIDN PELGDAEEDS ELAKPGEKEG WRNSMEKQSL VWKNTFWQGD IDNFHDDVTL 180
RNQRFIPFLN PRTPRKLTPY TVVLHGPAGV GKTTLAKKCM LDWTDCNLSP TLRYAFYLSC 240
KELSRMGPCS FAELISKDWP ELQDDIPSIL AQAQRILFVV DGLDELKVPP GALIQDICGD 300
WEKKKPVPVL LGSLLKRKML PRAALLVTTR PRALRDLQLL AQQPIYVRVE GFLEEDRRAY 360
FLRHFGDEDQ AMRAFELMRS NAALFQLGSA PAVCWIVCTT LKLQMEKGED PVPTCLTRTG 420
LFLRFLCSRF PQGAQLRGAL RTLSLLAAQG LWAQMSVFHR EDLERLGVQE SDLRLFLDGD 480
ILRQDRVSKG CYSFIHLSFQ QFLTALFYAL EKEEGEDRDG HAWDIGDVQK LLSGEERLKN 540
PDLIQVGHFL FGLANEKRAK ELEATFGCRM SPDIKQELLQ CKAHLHANKP LSVTDLKEVL 600
GCLYESQEEE LAKVVVAPFK EISIHLTNTS EVMHCSFSLK HCQDLQKLSL QVAKGVFLEN 660
YMDFELDIEF ERCTYLTIPN WARQDLRSLR LWTDFCSLFS SNSNLKFLEV KQSFLSDSSV 720
RILCDHVTRS TCHLQKVEIK NVTPDTAYRD FCLAFIGKKT LTHLTLAGHI EWERTMMLML 780
CDLLRNHKCN LQYLRLGGHC ATPEQWAEFF YVLKANQSLK HLRLSANVLL DEGAMLLYKT 840
MTRPKHFLQM LSLENCRLTE ASCKDLAAVL VVSKKLTHLC LAKNPIGDTG VKFLCEGLSY 900
PDCKLQTLVL QQCSITKLGC RYLSEALQEA CSLTNLDLSI NQIARGLWIL CQALENPNCN 960
LKHLRLWSCS LMPFYCQHLG SALLSNQKLE TLDLGQNHLW KSGIIKLFGV LRQRTGSLKI 1020
LRLKTYETNL EIKKLLEEVK EKNPKLTIDC NASGATAPPC CDFFC 1065
Gene Ontology
GO:0005524
; F:ATP binding; IEA:UniProtKB-KW.
Interpro
IPR004020
; DAPIN.
IPR011029
; DEATH-like_dom.
IPR007111
; NACHT_NTPase.
IPR027417
; P-loop_NTPase.
Pfam
PF02758
; PYRIN
SMART
PROSITE
PS50824
; DAPIN
PS50837
; NACHT
PRINTS