CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025835
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dihydropyrimidinase-like 2 variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
528SGRYIPRKPFPDFVYubiquitination[1]
567CEVSVTPKTVTPASSubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 628 AA 
Protein Sequence
IDFDSLSVGR GSGQVVAQQR DVAHLGPDPQ PPYSRQGRRA GGEPSVESGR KVEIRRASGK 60
EALQNINDQS DRLLIKGGKI VNDDQSFYAD IYMEDGLIKQ IGENLIVPGG VKTIEAHSRM 120
VIPGGIDVHT RFQMPDQGMT SADDFFQGTK AALAGGTTMI IDHVVPEPGT SLLAAFDQWR 180
EWADSKSCCD YSLHVDISEW HKGIQEEMEA LVKDHGVNSF LVYMAFKDRF QLTDCQIYEV 240
LSVIRDIGAI AQVHAENGDI IAEEQQRILD LGITGPEGHV LSRPEEVEAE AVNRAITIAN 300
QTNCPLYITK VMSKSSAEVI AQARKKGTVV YGEPITASLG TDGSHYWSKN WAKAAAFVTS 360
PPLSPDPTTP DFLNSLLSCG DLQVTGSAHC TFNTAQKAVG KDNFTLIPEG TNGTEERMSV 420
IWDKAVVTGK MDENQFVAVT STNAAKVFNL YPRKGRIAVG SDADLVIWDP DSVKTISAKT 480
HNSSLEYNIF EGMECRGSPL VVISQGKIVL EDGTLHVTEG SGRYIPRKPF PDFVYKRIKA 540
RSRLAELRGV PRGLYDGPVC EVSVTPKTVT PASSAKTSPA KQQAPPVRNL HQSGFSLSGA 600
QIDDNIPRRT TQRIVAPPGG RANITSLG 628 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0016812; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; IEA:InterPro.
 GO:0006208; P:pyrimidine nucleobase catabolic process; IEA:InterPro. 
Interpro
 IPR006680; Amidohydro_1.
 IPR011778; Hydantoinase/dihydroPyrase.
 IPR011059; Metal-dep_hydrolase_composite. 
Pfam
 PF01979; Amidohydro_1 
SMART
  
PROSITE
  
PRINTS