| Tag | Content |
|---|
| CPLM ID | CPLM-022740 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | A-kinase anchor protein 8-like |
Protein Synonyms/Alias | AKAP8-like protein; Neighbor of A-kinase-anchoring protein 95; Neighbor of AKAP95 |
Gene Name | Akap8l |
Gene Synonyms/Alias | Nakap; Nakap95 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 258 | FGFGNGMKQMRRTWK | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Could play a role in constitutive transport element (CTE)-mediated gene expression. Does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May regulate the initiation phase of DNA replication when associated with TMPO-beta (By similarity). |
Sequence Annotation | ZN_FING 390 414 C2H2 AKAP95-type 1.
ZN_FING 483 508 C2H2 AKAP95-type 2.
MOTIF 275 280 Nuclear localization signal (Potential).
MOTIF 363 365 Nuclear localization signal (Potential).
MOD_RES 258 258 N6-acetyllysine (By similarity).
MOD_RES 284 284 Phosphoserine (By similarity).
MOD_RES 293 293 Phosphothreonine (By similarity).
MOD_RES 298 298 Phosphoserine (By similarity). |
Keyword | Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 642 AA |
Protein Sequence | MSYTGFVQGS ETTLQSTYCD TSAQPTCDYG YGTWNSGTNR GYENYGYGYG YGQDNTTNYG 60
YGMATSHSWE MASSDTNANP SASGSASADS VLSRINQRLD MMPHLETDMI QGGVYGSGGG 120
ERYDSYEACD SRAILSERDL YRSSYDYGEL DPEMEMAYEG QYDAYRDQFR MRGGDTFGPR 180
AQGWARDARS GRPMASGYGR MWEDPMGARG QCMPGASRLP SLFSQNIIPE YGMFQGMRGG 240
GAFSGGSRFG FGFGNGMKQM RRTWKTWTTA DFRTKKKKRK QGGSPDEPDS KATRTDCSDN 300
SDSDNDEGTE GEAAEGTESA EAMEKGSRVD GEDEEGKEDG REEGKEDPEK GALTAQDESS 360
QAKRKLQASK KSQDKQKKRQ RDRMVERIQF VCSLCKYRTF YEDEMGSHLD SKFHKEHFKY 420
VGTKLPKQTA DFLQEYVTNK TKKTEELRKT VEDLDGLIQQ IYRDQDLTQE IAMEHFVKKV 480
EAAHCAACDL FIPMQFGIIQ KHLKTMDHNR NRRLMMEQSK KSSLMVARSI LNNKLISKKL 540
ERYLKGENPF TDNPEEEKEQ DEVEAGALDE GAPSEATELT EGVPAQPPVP LEPAPGTTTP 600
PPPPPPEEEE SPVPLLGGAL QCQIRGIPGL DMEDDEEGGG GP 642 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |