CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045566
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Aminomethyltransferase 
Protein Synonyms/Alias
  
Gene Name
 Amt 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
161ARFQDKVKEFQNRGLacetylation[1]
254LLKNPEVKLAGLAARacetylation[1]
306AMDFPGAKIIIPQLKacetylation[1]
313KIIIPQLKGEVQRRRacetylation[1]
391QQMTVVSKMPFVPTKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 The glycine cleavage system catalyzes the degradation of glycine (By similarity). 
Sequence Annotation
  
Keyword
 Aminotransferase; Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 403 AA 
Protein Sequence
MQRTVRVVAP LGFRLQAQPL VQSRPFSSVQ DGLRRTPLYD FHLAHGGKMV AFAGWSLPVQ 60
YRDSHVDSHL HTRRHCSLFD VSHMLQTKIF GCDRVRLMEN IVVGDIAELR PNQGHFRIFR 120
QLWRSTIPAL LHWEARDHRL YSLTSHAAEV PDLARFQDKV KEFQNRGLDV GLEVVDNALL 180
ALQGPTAAQV LQAGVTDDMR KLPFMTSAVM EVFGVSGCRV TRCGYTGEDG VEISVPAAGA 240
VHLATALLKN PEVKLAGLAA RDSLRLEAGL CLYGNDIDEH TTPVEGSLSW TLGKRRRVAM 300
DFPGAKIIIP QLKGEVQRRR VGLICEGAPM RAHSPILNTE GAVIGTVTSG CPSPSLKKNV 360
AMGYVAFKYS RPGTQLLVEV RRKQQMTVVS KMPFVPTKYY TLK 403 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0004047; F:aminomethyltransferase activity; IEA:EC.
 GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
 GO:0006546; P:glycine catabolic process; IEA:InterPro. 
Interpro
 IPR013977; GCV_T_C.
 IPR006222; GCV_T_N.
 IPR006223; GcvT.
 IPR027266; TrmE/GcvT_dom1. 
Pfam
 PF01571; GCV_T
 PF08669; GCV_T_C 
SMART
  
PROSITE
  
PRINTS