CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031465
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ57250, highly similar to Homo sapiens poly (ADP-ribose) polymerase family, member 10 (PARP10), mRNA 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
928RNATVYGKGVYFARRubiquitination[1, 2]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1037 AA 
Protein Sequence
MGCFPTHLMP RPRVAMAEAE AGVAVEVRGL PPAVPDELLT LYFENRRRSG GGPVLSWQRL 60
GCGGVLTFRE PADAERVLAQ ADHELHGAQL SLRPAPPRAP ARLLLQGLPP GTTPQRLEQH 120
IQALLRASGL PVQPCCALAS PRPDRALVQL PKPLSEADVR VLEEQAQNLG LEGTLVSLAR 180
VPQARAVRVV GDGASVDLLL LELYLENERR SGGGPLEDLQ RLPGPLGTVA SFQQWQVAER 240
VLQQEHRLQG SELSLVPHYD ILEPEELAEN TSGGDHPSTQ GPRATKHALL RTGGLVTALQ 300
GAGTVTMGSG EEPGQSGASL RTGPMVQGRG IMTTGSGQEP GQSGTSLRTG PMGSLGQAEQ 360
VSSMPMGSLE HEGLVSLRPV GLQEQEGPMS LGPVGSAGPV ETSKGLLGQE GLVEIAMDSP 420
EQEGLVGPME ITMGSLEKAG PVSPGCVKLA GQEGLVEMVL LMEPGAMRFL QLYHEDLLAG 480
LGDVALLPLE GPDMTGFRLC GAQASCQAAE EFLRSLLGSI SCHVLCLEHP GSARFLLGPE 540
GQHLLQGLEA QFQCVFGTER LATATLDTGL EEVDPTEALP VLPGNAHTLW TPDSTGGDQE 600
DVSLEEVREL LATLEGLDLD GEDWLPRELE EEGPQEQPEE EVTPGHEEEE PVAPSTVAPR 660
WLEEEAALQL ALHRSLEPQG QVAEQEEAAA LRQALTLSLL EQPPLEAEEP PDGGTDGKAQ 720
LVVHSAFEQD VEELDRALRA ALEVHVQEET VGPWRRTLPA ELRARLERCH GVSVALRGDC 780
TILRGFGAHP ARAARHLVAL LAGPWDQSLA FPLAASGPTL AGQTLKGPWN NLERLAENTG 840
EFQEVVRAFY DTLDAARSSI RVVRVERVSH PLLQQQYELY RERLLQRCER RPVEQVLYHG 900
TTAPAVPDIC AHGFNRSFCG RNATVYGKGV YFARRASLSV QDRYSPPNAD GHKAVFVARV 960
LTGDYGQGRR GLRAPPLRGP GHVLLRYDSA VDCICQPSIF VIFHDTQALP THLITCEHVP 1020
RASPDDPSGL PGRSPDT 1037 
Gene Ontology
 GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro. 
Interpro
 IPR012317; Poly(ADP-ribose)pol_cat_dom.
 IPR003903; Ubiquitin-int_motif. 
Pfam
 PF00644; PARP 
SMART
 SM00726; UIM 
PROSITE
 PS51059; PARP_CATALYTIC 
PRINTS