CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023463
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine/threonine-protein phosphatase 4 regulatory subunit 2 
Protein Synonyms/Alias
 PPP4R2-related protein 
Gene Name
 PPP4R2r 
Gene Synonyms/Alias
 CG2890 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
62EKLLSVIKHFNEDSPacetylation[1]
348EEVVESDKPDGKVAQacetylation[1]
352ESDKPDGKVAQLGDKacetylation[1]
454TETEAAEKSVSDEKQacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4) (By similarity). The probable PP4 complex Pp4- 19C-PPP4R2r-flfl (PPP4C-PPP4R2-PPP4R3) is required to prevent caspase induced cell death (in vitro). 
Sequence Annotation
 MOD_RES 68 68 Phosphoserine.
 MOD_RES 223 223 Phosphoserine.
 MOD_RES 226 226 Phosphoserine.
 MOD_RES 252 252 Phosphoserine.
 MOD_RES 602 602 Phosphothreonine.
 MOD_RES 603 603 Phosphoserine.  
Keyword
 Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 609 AA 
Protein Sequence
MVTMENSDEI MQILERFTDL KQKEIPKELE EYLQYVAKTG DTIFKWSSLK YLFREKLLSV 60
IKHFNEDSPR LEEIPNYPNV DPFNYETMKS SLLERLDLFN AAPFTVQRLC ELLIDPRKQY 120
SRIDKFMRAL EKNILVVSTI DPGRKRTESE NGDSLDSVVN GDLSMEVNID IEMENNNGNA 180
DEGSSPGAGS AGCAQKASCP RSDDNDQPKA KKAKLEIDGE ERSEASDETD TEVATRVKNE 240
KDEKNDNDET DSPHEAAEIE EPDEEVDEAD QETKTTKQPA YGSQKEGEQE ESFPSSADDE 300
AEDPMVSKSI EAEKELVAQE KKREEDKKVA IEPKEEIVKK EEVVESDKPD GKVAQLGDKA 360
VVKKSTPPAD GENQEPVKVK AENEKEEKKH APIKTEKQDD IDSTETDDAP SAEKPAEEKI 420
ASSESKPKTK SEDDPEAETK KSQPEKTETE AAEKSVSDEK QAAEPNAESE NRNDLTTSKA 480
TEAAQESVEK SPVEDASSPA VEDLAAATTP QSPLGAADSA AETPPAETGD DSQASPLVAA 540
VTPPVLALND QPMEDTPAEE EARVSPSATV EEVVMAESAN AGAMATEEAA KDDPAAMEID 600
DTSQEVMMQ 609 
Gene Ontology
 GO:0000278; P:mitotic cell cycle; IMP:FlyBase.
 GO:0022008; P:neurogenesis; IMP:FlyBase. 
Interpro
 IPR015267; PPP4R2. 
Pfam
 PF09184; PPP4R2 
SMART
  
PROSITE
  
PRINTS