UniProt Accession

 Q504N4_MOUSE; Q504N4 

Genbank Protein ID

 AC090648; BC094920; CH466523 

Genbank Nucleotide ID

 AAH94920.1; EDK99084.1 

Protein Name

 Deoxyguanosine kinase, isoform CRA_c 

Protein Synonyms/Alias

 Deoxyguanosine kinase, mitochondrial; Dguok protein 

Gene Name

 Dguok 

Gene Synonyms/Alias

 mCG_133572 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
135	GRLLQAEKSVRVFER	acetylation	[1]
135	GRLLQAEKSVRVFER	succinylation	[1]

Reference

 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

 ACT_SITE 141 141 Proton acceptor (By similarity).
 BINDING 70 70 Substrate (By similarity).
 BINDING 100 100 Substrate (By similarity).
 BINDING 111 111 Substrate (By similarity).
 BINDING 142 142 Substrate (By similarity).
 BINDING 147 147 Substrate (By similarity).
 BINDING 211 211 Substrate (By similarity).  

Keyword

 Complete proteome; Kinase; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 236 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:MGI.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004138; F:deoxyguanosine kinase activity; IDA:MGI.
 GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
 GO:0046070; P:dGTP metabolic process; IDA:MGI.
 GO:0010977; P:negative regulation of neuron projection development; IEA:Compara.
 GO:0006468; P:protein phosphorylation; IDA:MGI.
 GO:0046122; P:purine deoxyribonucleoside metabolic process; IEA:Compara. 

Interpro

 IPR002624; Deoxynucleoside_kinase.
 IPR027417; P-loop_NTPase. 

Pfam

 PF01712; dNK 

SMART

  

PROSITE

  

PRINTS