CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011292
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Survival factor 1 
Protein Synonyms/Alias
  
Gene Name
 SVF1 
Gene Synonyms/Alias
 SGI1; YDR346C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
3*****MLKWIKGGISacetylation[1]
161RRLTPGAKIGDDPATubiquitination[2]
350KDIKITFKGINTKVKacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Required for survival in response to oxidative stress. Involved in the diauxic shift. 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 481 AA 
Protein Sequence
MLKWIKGGIS AVTGMAEPEY GKDYIHSVAD RVKNKQPYRE TSREDFFWQA PDHTNVESVI 60
FYFSDLKTGI FGFAQVIHSN IIGLHTASQF TFRIFDSKNP EDLNIWTSTK LENFYIEGPN 120
FYADNLSVEL SEDGESYHIQ SSVCDLSVVD LHIRRLTPGA KIGDDPATYY GNNINEPWGS 180
MRHVFWPRNA CHGTIKVKKE VIPESDEEES SADEDDNEDE DEESGDSEEE SGSEEESDSE 240
EVEITYEDRT ITFKEEDPAI STFIMAFQGM KPHHAAKAWN FMFFHSEKYS AVLMEFTTPK 300
SYANTKISAG IITDDKEVLA MTTNNLVEHL NSEIDSVGWK VPKDIKITFK GINTKVKDEQ 360
LESENGTEQA LQGEDEKEDE KEDEEEEEYK NVAEENKICA VVEGPLNNLV ERIDVMGEIP 420
SFVKNIVSGV AGTKPFIYQY ADPKSSTLQI NGGEKIHGVA WTEVTFISES DVISEESYNE 480
A 481 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0034599; P:cellular response to oxidative stress; IMP:SGD. 
Interpro
 IPR013931; Oxidative_stress_survival. 
Pfam
 PF08622; Svf1 
SMART
  
PROSITE
  
PRINTS