| Tag | Content |
|---|
| CPLM ID | CPLM-010949 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 45 |
Protein Synonyms/Alias | BRC1744; Zinc finger protein 13; Zinc finger protein KOX5 |
Gene Name | ZNF45 |
Gene Synonyms/Alias | KOX5; ZNF13 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 117 | QITRELIKYQDSVVN | ubiquitination | [1] |
|
Reference | [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C. Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [ PMID: 21890473] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 8 78 KRAB.
ZN_FING 164 186 C2H2-type 1; degenerate.
ZN_FING 192 214 C2H2-type 2.
ZN_FING 220 247 C2H2-type 3.
ZN_FING 248 275 C2H2-type 4.
ZN_FING 276 298 C2H2-type 5.
ZN_FING 304 326 C2H2-type 6.
ZN_FING 332 354 C2H2-type 7.
ZN_FING 360 382 C2H2-type 8.
ZN_FING 388 410 C2H2-type 9.
ZN_FING 416 438 C2H2-type 10.
ZN_FING 444 466 C2H2-type 11.
ZN_FING 472 494 C2H2-type 12.
ZN_FING 500 522 C2H2-type 13.
ZN_FING 528 550 C2H2-type 14.
ZN_FING 556 578 C2H2-type 15.
ZN_FING 584 606 C2H2-type 16.
ZN_FING 612 634 C2H2-type 17.
ZN_FING 640 662 C2H2-type 18. |
Keyword | Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 682 AA |
Protein Sequence | MTKSKEAVTF KDVAVVFSEE ELQLLDLAQR KLYRDVMLEN FRNVVSVGHQ STPDGLPQLE 60
REEKLWMMKM ATQRDNSSGA KNLKEMETLQ EVGLRYLPHE ELFCSQIWQQ ITRELIKYQD 120
SVVNIQRTGC QLEKRDDLHY KDEGFSNQSS HLQVHRVHTG EKPYKGEHCV KSFSWSSHLQ 180
INQRAHAGEK PYKCEKCDNA FRRFSSLQAH QRVHSRAKSY TNDASYRSFS QRSHLPHHQR 240
VPTGENPYKY EECGRNVGKS SHCQAPLIVH TGEKPYKCEE CGVGFSQRSY LQVHLKVHTG 300
KKPYKCEECG KSFSWRSRLQ AHERIHTGEK PYKCNACGKS FSYSSHLNIH CRIHTGEKPY 360
KCEECGKGFS VGSHLQAHQI SHTGEKPYKC EECGKGFCRA SNLLDHQRGH TGEKPYQCDA 420
CGKGFSRSSD FNIHFRVHTG EKPYKCEECG KGFSQASNLL AHQRGHTGEK PYKCGTCGKG 480
FSRSSDLNVH CRIHTGEKPY KCERCGKAFS QFSSLQVHQR VHTGEKPYQC AECGKGFSVG 540
SQLQAHQRCH TGEKPYQCEE CGKGFCRASN FLAHRGVHTG EKPYRCDVCG KRFRQRSYLQ 600
AHQRVHTGER PYKCEECGKV FSWSSYLQAH QRVHTGEKPY KCEECGKGFS WSSSLIIHQR 660
VHADDEGDKD FPSSEDSHRK TR 682 |
Gene Ontology | GO:0005654; C:nucleoplasm; TAS:Reactome. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0007275; P:multicellular organismal development; TAS:ProtInc. GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |