| Tag | Content |
|---|
| CPLM ID | CPLM-000871 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vacuolar protein sorting-associated protein 52 homolog |
Protein Synonyms/Alias | SAC2 suppressor of actin mutations 2-like protein |
Gene Name | Vps52 |
Gene Synonyms/Alias | Are1; Sacm2l |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 584 | ERAADDSKEVESFQQ | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | May be involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (By similarity). |
Sequence Annotation | |
Keyword | Coiled coil; Complete proteome; Endosome; Golgi apparatus; Membrane; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 723 AA |
Protein Sequence | MAAAATMAAA ARELVLRAGA SDMEEEEGPL GAGSGLQEPL QLGELDITSD EFILDEVDVH 60
IQANLEDELV KEALKTGVDL RHYSKQVELE LQQIEQKSIR DYIQESENIA SLHNQITACD 120
AVLERMEQML GAFQSDLSSI SCEIRTLQEQ SGAMNIRLRN RQAVRGKLGE LVDGLVVPSA 180
LVTAILEAPV TEPRFLEQLQ ELDAKAAAVR EQEARGTAAC ADVRGVLDRL RVKAVTKIRE 240
FILQKIYSFR KPMTNYQIPQ TALLKYRFFY QFLLGNERAT AKEVRDEYVE TLSKIYLSYY 300
RSYVGRLMKV QYEEVAEKDD LMGVEDTAKK GFFSKPSLRS RNTIFTLGTR GAVISPAELE 360
APILVPHTAQ RGEQRYPFEA LFRSQHYALL DNSCREYLFI CEFFVVSGPA AHDLFHAVMG 420
RTLSMTLKHL ESYLADCYDA IAVFLCIHIV LRFRNIAAKR DVPALDRYWE QVLALLWPRF 480
ELILEMNVQS VRSTDPQRLG GLDTRPHYIT RRYAEFSSAL VSINQTIPNE RTLQLLGQLQ 540
VEVENFVLRV AAEFSSRKEQ LVFLINNYDM MLGVLMERAA DDSKEVESFQ QLLNARTQEF 600
IEELLSPPFG GLVAFVKEAE ALIERGQAER LRGEEARVTQ LIRGFGSSWK ASVESLSQDV 660
MRSFTNFRNG TSIIQGALTQ LIQLYHRFHR VLSQPQLRAL PARAELINIH HLMVELKKHK 720
PNF 723 |
Gene Ontology | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |