| Tag | Content |
|---|
| CPLM ID | CPLM-017239 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Trafficking protein particle complex subunit 12 |
Protein Synonyms/Alias | Tetratricopeptide repeat protein 15; TPR repeat protein 15 |
Gene Name | Trappc12 |
Gene Synonyms/Alias | Ttc15 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 663 | GDIKTAEKYFQDVEK | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May be involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage (By similarity). |
Sequence Annotation | REPEAT 607 640 TPR 1.
REPEAT 642 675 TPR 2.
REPEAT 682 715 TPR 3.
REPEAT 716 749 TPR 4.
MOD_RES 125 125 Phosphoserine.
MOD_RES 128 128 Phosphoserine.
MOD_RES 130 130 Phosphothreonine.
MOD_RES 234 234 Phosphoserine. |
Keyword | Complete proteome; ER-Golgi transport; Phosphoprotein; Reference proteome; Repeat; TPR repeat; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 797 AA |
Protein Sequence | METAKDGEQS PSEASPSAQA GPENIPEPMS REEESQPLYH EETIDLGGDE FASEENEPTS 60
EGSHNFGDKL NEHMMESVLI SDSPNNSEGD VGDLGCLQDV GEPPRGATDH RLPSSTDKEV 120
VDTLSNGSET DGDDTPRDIS DMTPDSRASL KEDSTQEDVT SMPALENAAT EEVGPKDSLA 180
PREEQTSEVS SNQSSSKDEP LPVCTIFSQA TATPSQPHLF LQDGFESQMV KSPSFSSTSE 240
TSAKTPPPMV QPSPSLSTFF GDTMSSNSLA SDFFDSFTTS TFISVSNPNA GSPVPEKLSS 300
LTAPVGEKSP DSTSPSYSTR MDRSESGVSR APLDVPESPK PFSQIQAVFA GSDDPFATAL 360
SMSEMDRRND AWLPSQATRE VLMSVATQQY GTVFIDKENL TMPGLKFDNI QGDAVKDLML 420
RFLGEKAAAK RQVLNASSVE QSFVGLKQLI SCRNWRAAVD LCGRLLTAHG QGYGKNGLPT 480
SHTTDSLQLW FVRLALLVKL GLFQNAEMEF EPFGNLDQPD LYYEYYPHVY PGRRGSMVPF 540
SMRILHAELQ QYLGNPQESL DRLHRVKTVC SKILANLEQG LAEDGGLSSV TQESRQASVQ 600
LWRSRLGRVL YSMANCLLLM KDYVLAVDAY LTVIKYYPEQ EPQLLSGIGR ILLQIGDIKT 660
AEKYFQDVEK VTQKLDGLQG KIMVLMNRAF LYLGQNNFAE AHKFFTEILR MDPTNAVANN 720
NAAVCLLYLG KLKDSLRQLE AMVQQDPRHY LHESVLFNLT TMYELESSRS MQKKQSLLEA 780
VASKEGDSFN TQCLKLA 797 |
Gene Ontology | GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell. GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. |
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Pfam | |
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