CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007931
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dolichyl-phosphate-mannose--protein mannosyltransferase 3 
Protein Synonyms/Alias
  
Gene Name
 PMT3 
Gene Synonyms/Alias
 YOR321W; O6148 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
12VATGYSEKSTDDDLIubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins (By similarity). 
Sequence Annotation
 DOMAIN 332 387 MIR 1.
 DOMAIN 401 457 MIR 2.
 DOMAIN 465 523 MIR 3.
 CARBOHYD 124 124 N-linked (GlcNAc...) (Potential).
 CARBOHYD 324 324 N-linked (GlcNAc...) (Potential).
 CARBOHYD 398 398 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Endoplasmic reticulum; Glycoprotein; Glycosyltransferase; Membrane; Reference proteome; Repeat; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 753 AA 
Protein Sequence
MPYRVATGYS EKSTDDDLIW RTPIVKEELE DADNFLKDDA ELYDKVKNES AVSHLDTIVM 60
PIIFTVLGMF TRMYKIGRNN HVVWDEAHFG KFGSYYLRHE FYHDVHPPLG KMLVGLSGYL 120
AGYNGSWDFP SGEVYPDYID YVKMRLFQAM FSSLCVPLAY FTGRAIGFSR LSVWLFTILV 180
IFENSYATLG KFILLDSMLL FFTVSSYFCL AKFHTMRKSP FSARWWLWLC LTGLNLGCAI 240
SVKMVGLFII SVVGIYTISE LWNLLSDRSV SWKVYVNHWL ARIFGLIIIP VCVFLLCFKI 300
HFDLLSNSGP GDSTMPSLFQ ASLNGTKVGK GPRDVALGSS IISIKNQALG GALLHSHVQP 360
FPEGSEQQQV TVYGYSDANN EWFFQRIRGV EPWTDAENKT IEFVKGGEMY RLMHRLTGKN 420
LHTHEVPAPI SKSEYEVSAY GDVDLGDYKD NWIIEIVEQV GEEDPTLLHP LSTSFRIKNS 480
ILGCYLAQSG KHLPEWGFRQ GEVVCLKHAS KRDKRTWWNI ETHENERLPQ GEDFVYPKTS 540
FFRNFMQLNS AMMATNNALV PNPEKFDGIA SSAWQWPTLN VGVRLCEWSE KSIKYFLLGS 600
PASVWPSSIA VCALIIHVIF LTLKWQRQCV ILSDPVERDV FVMAAFYPLL AWLLHYMPFV 660
VMSRVVYAHH YLPTLYFALM ILSYYFDMIT KRWATRNTGK FLRLGAYIVY GSIVIAGFFY 720
FSPFSFGMDG PVDDYAYLAW LPTWQIVEDI RNT 753 
Gene Ontology
 GO:0031502; C:dolichyl-phosphate-mannose-protein mannosyltransferase complex; IPI:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0004169; F:dolichyl-phosphate-mannose-protein mannosyltransferase activity; ISA:SGD.
 GO:0035269; P:protein O-linked mannosylation; IGI:SGD. 
Interpro
 IPR027005; GlyclTrfase_39_like.
 IPR003342; Glyco_trans_39.
 IPR016093; MIR_motif. 
Pfam
 PF02815; MIR
 PF02366; PMT 
SMART
 SM00472; MIR 
PROSITE
 PS50919; MIR 
PRINTS