CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038531
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cullin-5 
Protein Synonyms/Alias
  
Gene Name
 Cul5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
103NGVQNYMKYADAKLKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 651 AA 
Protein Sequence
MEDSIVRKLM LDTWNESIFS NIKNRLQDSA MKLVHAERLG EAFDSQLVIG VRESYVNLCS 60
NPEDKLQIYR DNFEKAYLDS TERFYRTQAP SYLQQNGVQN YMKYADAKLK EEEKRALRYL 120
ETRRECNSVE ALMECCVNAL VTSFKETILA ECQGMIKRNE TEKLHLMFSL MDKVPNGIEP 180
MLKDLEEHII SAGLADMVAA AETITTDSEK YVEQLLTLFN RFSKLVKEAF QDDPRFLTAR 240
DKAYKAVVND ATIFKLELPL KQKGVGLKTQ PESKCPELLA NYCDMLLRKT PLSKKLTSEE 300
IEAKLKEVLL VLKYVQNKDV FMRYHKAHLT RRLILDISAD SEIEENMVEW LREVGMPADY 360
VNKLARMFQD IKVSEDLNQA FKEMHKNNKL ALPADSVNIK ILNAGAWSRS SEKVFVSLPT 420
ELEDLIPEVE EFYKKNHSGR KLHWHHLMSN GIITFKNEVG QYDLEVTTFQ LAVLFAWNQR 480
PREKISFENL KLATELPDAE LRRTLWSLVA FPKLKRQVLL YDPQVNSPKD FTEGTLFSVN 540
QDFSLIKNAK VQKRGKINLI GRLQLTTERM REEENEGIVQ LRILRTQEAI IQIMKMRKKI 600
SNAQLQTELV EILKNMFLPQ KKMIKEQMEW LIEHRYIRRD EADINTFIYM A 651 
Gene Ontology
 GO:0031466; C:Cul5-RING ubiquitin ligase complex; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0051480; P:cytosolic calcium ion homeostasis; IEA:Compara.
 GO:0006970; P:response to osmotic stress; IEA:Compara.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR016157; Cullin_CS.
 IPR016158; Cullin_homology.
 IPR001373; Cullin_N.
 IPR019559; Cullin_neddylation_domain.
 IPR016159; Cullin_repeat-like_dom.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00888; Cullin
 PF10557; Cullin_Nedd8 
SMART
 SM00182; CULLIN
 SM00884; Cullin_Nedd8 
PROSITE
 PS01256; CULLIN_1
 PS50069; CULLIN_2 
PRINTS