UniProt Accession

 B7Z7B0_HUMAN; B7Z7B0 

Genbank Protein ID

 AC073063; AK301745 

Genbank Nucleotide ID

 BAH13546.1 

Protein Name

 Cleavage and polyadenylation-specificity factor subunit 4 

Protein Synonyms/Alias

 cDNA FLJ52791, highly similar to Cleavage and polyadenylation specificityfactor 30 kDa subunit 

Gene Name

 CPSF4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
16	GEKTVVCKHWLRGLC	ubiquitination	[1]
55	KFGECSNKECPFLHI	ubiquitination	[1]
67	LHIDPESKIKDCPWY	ubiquitination	[1]
69	IDPESKIKDCPWYDR	ubiquitination	[1]
80	WYDRGFCKHGPLCRH	acetylation	[2]
80	WYDRGFCKHGPLCRH	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 191 AA 

Protein Sequence

Gene Ontology

 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR000571; Znf_CCCH.
 IPR001878; Znf_CCHC. 

Pfam

 PF00642; zf-CCCH
 PF00098; zf-CCHC 

SMART

 SM00343; ZnF_C2HC
 SM00356; ZnF_C3H1 

PROSITE

 PS50103; ZF_C3H1
 PS50158; ZF_CCHC 

PRINTS