UniProt Accession

 Q6NXR6_HUMAN; Q6NXR6; A6NJ55 

Genbank Protein ID

 AL110504; AL132819; BC066931 

Genbank Nucleotide ID

 AAH66931.1 

Protein Name

 Histone-lysine N-methyltransferase setd3 

Protein Synonyms/Alias

 SETD3 protein 

Gene Name

 SETD3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
74	LSVTFDGKREDYFPD	ubiquitination	[1]
115	LRATRDIKAEELFLW	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 292 AA 

Protein Sequence

Gene Ontology

 GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IEA:InterPro.
 GO:0003713; F:transcription coactivator activity; IEA:InterPro. 

Interpro

 IPR025785; Hist-Lys_N-MeTrfase_SETD3.
 IPR001214; SET_dom. 

Pfam

 PF00856; SET 

SMART

  

PROSITE

 PS51565; SAM_MT43_SETD3 

PRINTS