CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025272
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Eps8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
709QLPVDRRKSQMEEVQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 847 AA 
Protein Sequence
MLSQSCLDSC LDEFYLSSAG RGVRAGMNGH MSNRSSGYGV YPSQLNGYGS SPPYSQMDRE 60
HSSRTSAKAL YEQRKNYARD SVSSVSDVSQ YRVEHLTTFV LDRKDAMITV EDGIRKLKLL 120
DAKGKVWTQD MILQVDDRAV SLIDLESKNE LENFPLNTIS HCQAVVHACS YDSILALVCK 180
EPTQSKPDLH LFQCDEVKAN LISEDIESAI SDSKGGKQKR RPEALRMIAK ADPGIPPPPR 240
APAPVPPGTV TQVDVRSRVA AWSAWAADQG DFEKPRQYHE QEETPEMMAA RIDRDVQILN 300
HILDDIEFFI TKLQKAAEAF SELSKRKKSK KSKRKGPGEG VLTLRAKPPP PDEFVDCFQK 360
FKHGFNLLAK LKSHIQNPSA SDLVHFLFTP LNMVVQATGG PELASSVLSP LLTKDTVDFL 420
NYTATAEERK LWMSLGDSWV KVRAEWPKEQ FIPPYVPRFR NGWEPPMLNF MGAPTEQDMY 480
QLAESVANAE HQRKQDSKRL STEHSNVSDY PPADGYAYSS SMYHRGPHAD HGEAAMPFKS 540
TPNHQVDRNY DAVKTQPKKY AKSKYDFVAR NSSELSVMKD DVLEILDDRR QWWKVRNASG 600
DSGFVPNNIL DIMRTPESGV GRADPPYTHT IQKQRTEYGL RSADTPSAPS PPPTPAPVPV 660
PLPPSVPAPV SVPKVPANVT RQNSSSSDSG GSIVRDSQRY KQLPVDRRKS QMEEVQDELF 720
QRLTIGRSAA QRKFHVPRQN VPVINITYDS SPEEVKTWLQ SKGFNPVTVN SLGVLNGAQL 780
FSLNKDELRS VCPEGARVFN QITVQKAALE DSNGSSELQE IMRRRQEKIS AAASDSGVES 840
FDEGSSH 847 
Gene Ontology
 GO:0017146; C:N-methyl-D-aspartate selective glutamate receptor complex; IDA:MGI.
 GO:0014069; C:postsynaptic density; IDA:MGI.
 GO:0031532; P:actin cytoskeleton reorganization; IMP:MGI.
 GO:0051017; P:actin filament bundle assembly; IGI:MGI.
 GO:0008344; P:adult locomotory behavior; IMP:MGI.
 GO:0048149; P:behavioral response to ethanol; IMP:MGI. 
Interpro
 IPR011993; PH_like_dom.
 IPR013625; PTB.
 IPR006020; PTyr_interaction_dom.
 IPR001452; SH3_domain. 
Pfam
 PF08416; PTB
 PF00018; SH3_1 
SMART
 SM00462; PTB
 SM00326; SH3 
PROSITE
 PS50002; SH3 
PRINTS