CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021780
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein 
Protein Synonyms/Alias
  
Gene Name
 Herpud2 
Gene Synonyms/Alias
 MNCb-2040 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
70LPDHLQLKDILRKQDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Could be involved in the unfolded protein response (UPR) pathway (By similarity). 
Sequence Annotation
 DOMAIN 10 89 Ubiquitin-like.  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Unfolded protein response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 404 AA 
Protein Sequence
MDQSGMEIPV TLIIKAPNQK YSDQTISCFL NWTVGKLKTH LSNVYPSKPL TKDQRLVYSG 60
RLLPDHLQLK DILRKQDEYH MVHLVCASRS PPSSPKSSTD RGSHEALASS TSSNSDHSDS 120
TTPSPSQESL SLVTGSSEGL RQRTLSQAQT DPAQSHQFPY VIQGNVDHQF PGQGVPPAFP 180
VYPALSPLQM LWWQQMYAHQ YYMQYQAAVS AQATSSAGSA QRAASSPLNL AHVPGEEPPP 240
APNLVAQENG PMNENVQMNA QGGPVLNEED LNRDWLDWVY TFSRAAVLLS IVYFYSSFSR 300
FIMVMGAMLL VYLHQAGWFP FRQEGGQQQA PNNVDANNDG HNANNLELEE MERLMDDGLE 360
DESGEDAGED ASAAQRPGLM ASAWSFITTF FTSLIPEGPP QVAN 404 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
 GO:0007283; P:spermatogenesis; IEP:BHF-UCL. 
Interpro
 IPR000626; Ubiquitin.
 IPR019955; Ubiquitin_supergroup. 
Pfam
 PF00240; ubiquitin 
SMART
 SM00213; UBQ 
PROSITE
 PS50053; UBIQUITIN_2 
PRINTS