CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033485
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable serine carboxypeptidase CPVL 
Protein Synonyms/Alias
  
Gene Name
 CPVL 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
199KQKKYFQKQCHECIEubiquitination[1]
210ECIEHIRKQNWFEAFubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 244 AA 
Protein Sequence
MKSYAGFLTV NKTYNSNLFF WFFPAQIQPE DAPVVLWLQG GPGGSSMFGL FVEHGPYVVT 60
SNMTLRDRDF PWTTTLSMLY IDNPVGTGFS FTDDTHGYAV NEDDVARDLY SALIQFFQIF 120
PEYKNNDFYV TGESYAGKYV PAIAHLIHSL NPVREVKINL NGIAIGDGYS DPESIIGGYA 180
EFLYQIGLLD EKQKKYFQKQ CHECIEHIRK QNWFEAFEIL DKLLDGDLTS DPSYFQNVTG 240
CSNY 244 
Gene Ontology
 GO:0004185; F:serine-type carboxypeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR001563; Peptidase_S10.
 IPR018202; Peptidase_S10_AS. 
Pfam
 PF00450; Peptidase_S10 
SMART
  
PROSITE
 PS00131; CARBOXYPEPT_SER_SER 
PRINTS
 PR00724; CRBOXYPTASEC.