CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019032
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Collagen alpha-1(XXVI) chain 
Protein Synonyms/Alias
 Alpha-1 type XXVI collagen; EMI domain-containing protein 2; Emilin and multimerin domain-containing protein 2; Emu2 
Gene Name
 COL26A1 
Gene Synonyms/Alias
 EMID2; EMU2 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
355VKGEEGEKAATAEGEacetylation[1]
372QQLREALKILAERVLacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 DOMAIN 52 128 EMI.
 DOMAIN 199 267 Collagen-like 1.
 DOMAIN 302 355 Collagen-like 2.
 CARBOHYD 70 70 N-linked (GlcNAc...) (Potential).
 CARBOHYD 132 132 N-linked (GlcNAc...) (Potential).
 DISULFID 56 118 By similarity.
 DISULFID 83 89 By similarity.
 DISULFID 117 126 By similarity.  
Keyword
 Alternative splicing; Collagen; Complete proteome; Disulfide bond; Extracellular matrix; Glycoprotein; Hydroxylation; Polymorphism; Reference proteome; Repeat; Secreted; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 441 AA 
Protein Sequence
MKLALLLPWA CCCLCGSALA TGFLYPFSAA ALQQHGYPEP GAGSPGSGYA SRRHWCHHTV 60
TRTVSCQVQN GSETVVQRVY QSCRWPGPCA NLVSYRTLIR PTYRVSYRTV TVLEWRCCPG 120
FTGSNCDEEC MNCTRLSDMS ERLTTLEAKV LLLEAAERPS SPDNDLPAPE STPPTWNEDF 180
LPDAIPLAHP VPRQRRPTGP AGPPGQTGPP GPAGPPGSKG DRGQTGEKGP AGPPGLLGPP 240
GPRGLPGEMG RPGPPGPPGP AGNPGPSPNS PQGALYSLQP PTDKDNGDSR LASAIVDTVL 300
AGVPGPRGPP GPPGPPGPRG PPGPPGTPGS QGLAGERGTV GPSGEPGVKG EEGEKAATAE 360
GEGVQQLREA LKILAERVLI LEHMIGIHDP LASPEGGSGQ DAALRANLKM KRGGAQPDGV 420
LAALLGPDPG QKSVDQASSR K 441 
Gene Ontology
 GO:0005581; C:collagen; IEA:UniProtKB-KW.
 GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.
 GO:0005576; C:extracellular region; TAS:Reactome.
 GO:0005886; C:plasma membrane; TAS:Reactome.
 GO:0030574; P:collagen catabolic process; TAS:Reactome.
 GO:0022617; P:extracellular matrix disassembly; TAS:Reactome. 
Interpro
 IPR008160; Collagen.
 IPR011489; EMI_domain. 
Pfam
 PF01391; Collagen
 PF07546; EMI 
SMART
  
PROSITE
 PS51041; EMI 
PRINTS