| Tag | Content |
|---|
| CPLM ID | CPLM-006265 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | S-formylglutathione hydrolase YeiG |
Protein Synonyms/Alias | FGH |
Gene Name | yeiG |
Gene Synonyms/Alias | b2154; JW2141 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 87 | DTSPRGEKVANDDGY | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate. Shows also esterase activity against alpha-naphthyl acetate, lactoylglutathione, palmitoyl-CoA and several pNP-esters of short chain fatty acids. |
Sequence Annotation | ACT_SITE 145 145 Charge relay system (Probable).
ACT_SITE 223 223 Charge relay system (Probable).
ACT_SITE 256 256 Charge relay system (Probable). |
Keyword | Complete proteome; Hydrolase; Reference proteome; Serine esterase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 278 AA |
Protein Sequence | MEMLEEHRCF EGWQQRWRHD SSTLNCPMTF SIFLPPPRDH TPPPVLYWLS GLTCNDENFT 60
TKAGAQRVAA ELGIVLVMPD TSPRGEKVAN DDGYDLGQGA GFYLNATQPP WATHYRMYDY 120
LRDELPALVQ SQFNVSDRCA ISGHSMGGHG ALIMALKNPG KYTSVSAFAP IVNPCSVPWG 180
IKAFSSYLGE DKNAWLEWDS CALMYASNAQ DAIPTLIDQG DNDQFLADQL QPAVLAEAAR 240
QKAWPMTLRI QPGYDHSYYF IASFIEDHLR FHAQYLLK 278 |
Gene Ontology | GO:0004091; F:carboxylesterase activity; IEA:UniProtKB-KW. GO:0004416; F:hydroxyacylglutathione hydrolase activity; IDA:EcoCyc. GO:0018738; F:S-formylglutathione hydrolase activity; IDA:EcoCyc. GO:0046294; P:formaldehyde catabolic process; IMP:EcoCyc. |
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