CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027971
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Brd8 
Protein Synonyms/Alias
  
Gene Name
 Brd8 
Gene Synonyms/Alias
 CG14514; Dmel_CG14514 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
432EVIDFEDKLDALKREacetylation[1]
591SGKDTAGKPVTMQEKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 872 AA 
Protein Sequence
MSAGVQERLQ LSRMPLDTWS KREQLILASA VSCSGDQNWI TVSRTLKTIC GNGSSNRPAD 60
WFSQKNCAMQ YGNLLESVEA TKRKKRSSES SAGVSSPATV ETPTELLLRR LTEERQAEIK 120
AQMRQDQETY RRIQREIESL QSDAVTEQEL QDMWLEIEKE QEARRIEEMK LENRMREREQ 180
RKKDLASNWR NSSLAVKRSN QAADTTSVDM DVEDINTSGN GKQQTGPSPL LTSLLKSPTG 240
NAPATPTPGG AAPAAGGTGS VARATAPTIT SLLTSGPSSA VANQPVITMK SPTDAAFMSR 300
PITGPPASEA STTPTLERSP SQAAPTLSML LEKNMAAAKA NESGSLVKPE GSGNQEQGVD 360
EATSSAAGTA DSDEADPNEA QLLEVFKNID QIIDDIDIDM ASVIDDEILK NVDDVVASPS 420
NDKAEVIDFE DKLDALKREQ SKSSPASDKP KSVELVIGSS DDSNDNIPLA AVASQESKDR 480
GQSGGESTRG TEDAESEPLT SEVAVEEIGE TITIISTSSE DTAGSPPTKM EEDGATDSLP 540
KKEDAAEDKS EQESSSQGQN KAGGSTDEPE LIDHQATREA QSKSGKDTAG KPVTMQEKTT 600
TQSAPVPVDL HDTDEESSSL TDSSKHDDHP RSAKAKPPAL KLALDDSKSE LELSGTPQPP 660
SAPARTPLLR KLPHRDRSES PMVDDDATTA SDHSTARSTR RRCSSTPVID SIPNSPASSE 720
HTDDRRETRA ASKKLFLSIY AMLLDSKHAA PFKRPFHDEH AQRHADLCLR PMDFPTIKRN 780
IDSGFIRSLS ELHRDVLLMA HNVLVAYKPH TAQHKTARLF VQDCQAIKEF SQLPDVQAGI 840
TATPVSNTGS LRADKSSGSK ARSGSRKSQR HH 872 
Gene Ontology
 GO:0010629; P:negative regulation of gene expression; IMP:FlyBase. 
Interpro
 IPR001487; Bromodomain. 
Pfam
 PF00439; Bromodomain 
SMART
 SM00297; BROMO 
PROSITE
 PS50014; BROMODOMAIN_2 
PRINTS