CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028357
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sodium/hydrogen exchanger 
Protein Synonyms/Alias
  
Gene Name
 Slc9a6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
561DNERRTTKAESAWLFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Antiport; Complete proteome; Ion transport; Membrane; Reference proteome; Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 702 AA 
Protein Sequence
MAGARRGWRL APVRRGVCGP RARPLMRPLW LLFAVSFFGW TGALDGSGGT TRAMDEEIVS 60
EKQAEESHRQ DSANLLIFIL LLTLTILTIW LFKHRRARFL HETGLAMIYG LLVGLVLRYG 120
IHVPSDVNNV TLSCEVQSSP TTLLVNVSGK FYEYTLKGEI SSHELNNVQD NEMLRKVTFD 180
PEVFFNILLP PIIFYAGYSL KRRHFFRNLG SILAYAFLGT AISCFVIGSI MYGCVTLMKV 240
TGQLAGDFYF TDCLLFGAIV SATDPVTVLA IFHELQVDVE LYALLFGESV LNDAVAIVLS 300
SSIVAYQPAG DNSHTFDVTA MFKSIGIFLG IFSGSFAMGA ATGVVTALVT KFTKLREFQL 360
LETGLFFLMS WSTFLLAEAW GFTGVVAVLF CGITQAHYTY NNLSTESQHR TKQLFELLNF 420
LAENFIFSYM GLTLFTFQNH VFNPTFVVGA FIAIFLGRAA NIYPLSLLLN LGRRSKIGSN 480
FQHMMMFAGL RGAMAFALAI RDTATYARQM MFSTTLLIVF FTVWVFGGGT TAMLSCLHIR 540
VGVDSDQEHL GVPDNERRTT KAESAWLFRM WYNFDHNYLK PLLTHSGPPL TTTLPACCGP 600
IARCLTSPQA YENQEQLKDD DSDLILNDGD ISLTYGDSTV NTESATASAP RRFMGNSSED 660
ALDRELTFGD HELVIRGTRL VLPMDDSEPA LNSLDDTRHS PA 702 
Gene Ontology
 GO:0031901; C:early endosome membrane; IEA:Compara.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0055038; C:recycling endosome membrane; IEA:Compara.
 GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro.
 GO:0006885; P:regulation of pH; IEA:InterPro. 
Interpro
 IPR006153; Cation/H_exchanger.
 IPR018422; Cation/H_exchanger_CPA1.
 IPR002090; Na/H_exchanger_6.
 IPR004709; NaH_exchanger. 
Pfam
 PF00999; Na_H_Exchanger 
SMART
  
PROSITE
  
PRINTS
 PR01084; NAHEXCHNGR.
 PR01088; NAHEXCHNGR6.