CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031569
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Adenosine deaminase CECR1 
Protein Synonyms/Alias
 cDNA FLJ58672, highly similar to Cat eye syndrome critical region protein 1 
Gene Name
 CECR1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
13GRLVLNTKEELANERubiquitination[1, 2]
25NERLMTLKIAEMKEAubiquitination[1, 2]
30TLKIAEMKEAMRTLIubiquitination[1, 2]
116PTPRPSEKCSKWILLubiquitination[1]
119RPSEKCSKWILLEDYubiquitination[1]
225HDEEWSVKTYQEVAQubiquitination[1]
233TYQEVAQKFVETHPEubiquitination[1]
245HPEFIGIKIIYSDHRubiquitination[1]
254IYSDHRSKDVAVIAEubiquitination[1, 2]
304EALMIPAKDGVKLPYubiquitination[1, 2]
308IPAKDGVKLPYFFHAubiquitination[1]
348GHGFALSKHPAVRTYubiquitination[1, 2]
359VRTYSWKKDIPIEVCubiquitination[1, 2]
374PISNQVLKLVSDLRNubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 469 AA 
Protein Sequence
MMRLGGRLVL NTKEELANER LMTLKIAEMK EAMRTLIFPP SMHFFQAKHL IERSQVFNIL 60
RMMPKGAALH LHDIGIVTMD WLVRNVTYRP HCHICFTPRG IMQFRFAHPT PRPSEKCSKW 120
ILLEDYRKRV QNVTEFDDSL LRNFTLVTQH PEVIYTNQNV VWSKFETIFF TISGLIHYAP 180
VFRDYVFRSM QEFYEDNVLY MEIRARLLPV YELSGEHHDE EWSVKTYQEV AQKFVETHPE 240
FIGIKIIYSD HRSKDVAVIA ESIRMAMGLR IKFPTVVAGF DLVGHEDTGH SLHDYKEALM 300
IPAKDGVKLP YFFHAGETDW QGTSIDRNIL DALMLNTTRI GHGFALSKHP AVRTYSWKKD 360
IPIEVCPISN QVLKLVSDLR NHPVATLMAT GHPMVISSDD PAMFGAKGLS YDFYEVFMGI 420
GGMKADLRTL KQLAMNSIKY STLLESEKNT FMEIWKKRWD KFIADVATK 469 
Gene Ontology
 GO:0005615; C:extracellular space; IEA:InterPro.
 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0019239; F:deaminase activity; IEA:InterPro.
 GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; IEA:InterPro. 
Interpro
 IPR001365; A/AMP_deaminase_dom.
 IPR013659; A_deaminase_N.
 IPR006331; Ad_deam-like. 
Pfam
 PF00962; A_deaminase
 PF08451; A_deaminase_N 
SMART
  
PROSITE
  
PRINTS