CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032338
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tyrosyl-DNA phosphodiesterase 1 
Protein Synonyms/Alias
 Tyrosyl-DNA phosphodiesterase 1, isoform CRA_b 
Gene Name
 Tdp1 
Gene Synonyms/Alias
 mCG_14730 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
127PDVTTAQKVVDRSPPacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 609 AA 
Protein Sequence
MSQESSYGKW TISSSDESED EKPKPDKPSA SSHPQAGQGV SKELIYTCSE ARKVAHKRQI 60
SPVKFNDADS VLPHKKQKSD SPEGLGWCLS SSDDDQQPDV TQQEQPKRVL PQEKKHVSSP 120
DVTTAQKVVD RSPPASLRPQ RADDEYETSG EGQDIWDMLD KGNPFQFYLT RVSGIKAKYN 180
SKALHIKDIL SPLFGTLVSS AQFNYCFDVD WLIKQYPPEF RKNPILLVHG DKREAKADLH 240
AQAKPYANIS LCQAKLDIAF GTHHTKMMLL LYEEGLRVVI HTSNLIREDW HQKTQGIWLS 300
PLYPRIDQGS HTAGESSTRF KADLTSYLTA YNAPPLQEWI DIIQEHDLSE TNVYLIGSTP 360
GRFQGSHRDN WGHFRLRKLL QAHAPSTPKG ECWPIVGQFS SIGSLGPDES KWLCSEFKDS 420
LLALREEGRP PGKSAVPLHL IYPSVENVRT SLEGYPAGGS LPYSIQTAEK QRWLHSYFHK 480
WSAETSGRSN AMPHIKTYMR PSPDFSKLAW FLVTSANLSK AAWGALEKNG TQLMIRSYEL 540
GVLFLPSAFG LDTFKVKQKF FSSSCEPTAS FPVPYDLPPE LYGSKDRPWI WNIPYVKAPD 600
THGNMWVPS 609 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0017005; F:3'-tyrosyl-DNA phosphodiesterase activity; IEA:Compara.
 GO:0003690; F:double-stranded DNA binding; IEA:Compara.
 GO:0003697; F:single-stranded DNA binding; IEA:Compara.
 GO:0006302; P:double-strand break repair; IEA:Compara.
 GO:0000012; P:single strand break repair; IMP:MGI. 
Interpro
 IPR027415; TDP_C.
 IPR010347; Tyr-DNA_phospho. 
Pfam
 PF06087; Tyr-DNA_phospho 
SMART
  
PROSITE
  
PRINTS