| Tag | Content |
|---|
| CPLM ID | CPLM-019894 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | RNA-binding protein 10 |
Protein Synonyms/Alias | RNA-binding motif protein 10 |
Gene Name | Rbm10 |
Gene Synonyms/Alias | Kiaa0122 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 54 | EYGSQEGKHEYDDSS | acetylation | [1] |
|
Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | Not known. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). |
Sequence Annotation | DOMAIN 129 209 RRM 1.
DOMAIN 300 384 RRM 2.
DOMAIN 858 904 G-patch.
ZN_FING 212 242 RanBP2-type.
ZN_FING 759 784 C2H2-type; atypical.
MOD_RES 61 61 Phosphoserine (By similarity).
MOD_RES 89 89 Phosphoserine (By similarity).
MOD_RES 383 383 N6-acetyllysine (By similarity).
MOD_RES 718 718 Phosphoserine (By similarity).
MOD_RES 723 723 Phosphoserine (By similarity).
MOD_RES 733 733 Phosphoserine.
MOD_RES 736 736 Phosphoserine.
MOD_RES 738 738 Phosphoserine.
MOD_RES 781 781 Phosphoserine (By similarity).
MOD_RES 797 797 Phosphoserine (By similarity). |
Keyword | Acetylation; Alternative splicing; Complete proteome; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; RNA-binding; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 930 AA |
Protein Sequence | MEYERRGGRG DRTGRYGATD RSQDDSGENR SRDHDYRDMD YRSYPREYGS QEGKHEYDDS 60
SEEQSAEIRG QLQSHGVQAR EVRLMRNKSS GQSRGFAFVE FSHLQDATRW MEANQHSLNI 120
LGQKVSMHYS DPKPKINEDW LCNKCGVQNF KRREKCFKCG VPKSEAEQKL PLGTRLDQQA 180
LPLGGRELSQ GLLPLPQPYQ AQGVLTSQAL SQGSEPSSEN ANDTIILRNL NPHSTMDSIL 240
GALAPYAVLS SSNVRVIKDK QTQLNRGFAF IQLSTIVEAA QLLQILQALH PPLTIDGKTI 300
NVEFAKGSKR DMASNEGSRI NAASVASTAI AAAQWAISQA SQGGESAWAA PEEPPVDYSY 360
YQQDEGYGSS QGTDSLYAHG YLKNSKGPGM TGTKGDPAGT GPEASLEAGA DSVSLQAFSR 420
AQPGAAPGLY QQSAEGSSGQ STATNSQSYT IISPAVLKAE LQSPTQPSSS AFPPATSPTA 480
PEAYSQYPVP DVSTYQYDET SGYYYDPQTG LYYDPNSQYY YNAQSQQYLY WDGERRTYIP 540
ALEQSADGHK DTGASSKEGK EKKEKHKTKT AQQIAKDMER WARSLNKQKE NFKNSFQPIS 600
ALRDDERRES ATADAGYAIL EKKGALAERQ HTSMDLPKLA SDDRPSPPRG LVAAYSGESD 660
SEEEQERGGP EREEKLTDWQ KLACLLCRRQ FPSKEALIRH QQLSGLHKQN LEIHRRAHLS 720
ENELEALEKN DMEQMKYRDR AAERREKYGI PEPPEPKRRK YGGISTASVD FEQPTRDGLG 780
SDNIGSRMLQ AMGWKEGSGL GRKKQGIVTP IEAQTRVRGS GLGARGSSYG VTSTESYKET 840
LHKTMVTRFN EAQ 853 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0000166; F:nucleotide binding; IEA:InterPro. GO:0003723; F:RNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:MGI. GO:0008285; P:negative regulation of cell proliferation; IDA:MGI. GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI. GO:0034393; P:positive regulation of smooth muscle cell apoptotic process; IDA:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |