UniProt Accession

 SODM_DROME; Q00637; Q9V7T8 

Genbank Protein ID

 L18947; L34276; AE013599; BT004505; X64062 

Genbank Nucleotide ID

 AAA20533.1; AAA28694.1; AAF57955.1; AAO42669.1; CAA45418.1 

Protein Name

 Superoxide dismutase [Mn], mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 Sod2 

Gene Synonyms/Alias

 CG8905 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
73	KSKSDTTKLIQLAPA	acetylation	[1]
118	KAIESQWKSLEEFKK	acetylation	[1]
124	WKSLEEFKKELTTLT	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. 

Sequence Annotation

 METAL 43 43 Manganese (By similarity).
 METAL 91 91 Manganese (By similarity).
 METAL 175 175 Manganese (By similarity).
 METAL 179 179 Manganese (By similarity).  

Keyword

 Complete proteome; Manganese; Metal-binding; Mitochondrion; Oxidoreductase; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 217 AA 

Protein Sequence

Gene Ontology

 GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
 GO:0016209; F:antioxidant activity; NAS:FlyBase.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004784; F:superoxide dismutase activity; IEA:EC.
 GO:0008340; P:determination of adult lifespan; IMP:FlyBase.
 GO:0035206; P:regulation of hemocyte proliferation; IMP:FlyBase.
 GO:0019222; P:regulation of metabolic process; IMP:FlyBase.
 GO:0006801; P:superoxide metabolic process; IEA:InterPro. 

Interpro

 IPR001189; Mn/Fe_SOD.
 IPR019833; Mn/Fe_SOD_BS.
 IPR019832; Mn/Fe_SOD_C.
 IPR019831; Mn/Fe_SOD_N. 

Pfam

 PF02777; Sod_Fe_C
 PF00081; Sod_Fe_N 

SMART

  

PROSITE

 PS00088; SOD_MN 

PRINTS

 PR01703; MNSODISMTASE.