UniProt Accession

 RAB8B_RAT; P70550 

Genbank Protein ID

 U53475 

Genbank Nucleotide ID

 AAA99782.1 

Protein Name

 Ras-related protein Rab-8B 

Protein Synonyms/Alias

  

Gene Name

 Rab8b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
138	VSKERGEKLAIDYGI	acetylation	[1]
138	VSKERGEKLAIDYGI	ubiquitination	[2]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 May be involved in vesicular trafficking and neurotransmitter release (By similarity). May participate in cell junction dynamics in Sertoli cells. 

Sequence Annotation

 NP_BIND 15 22 GTP (By similarity).
 NP_BIND 63 67 GTP (By similarity).
 NP_BIND 121 124 GTP (By similarity).
 MOTIF 37 45 Effector region (By similarity).
 MOD_RES 204 204 Cysteine methyl ester (Potential).
 LIPID 204 204 S-geranylgeranyl cysteine (By  

Keyword

 Cell membrane; Complete proteome; Cytoplasmic vesicle; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Prenylation; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 207 AA 

Protein Sequence

Gene Ontology

 GO:0051286; C:cell tip; IDA:RGD.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
 GO:0005778; C:peroxisomal membrane; IEA:Compara.
 GO:0045335; C:phagocytic vesicle; ISS:UniProtKB.
 GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; IDA:RGD.
 GO:0019003; F:GDP binding; ISS:UniProtKB.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0034332; P:adherens junction organization; IDA:UniProtKB.
 GO:0031346; P:positive regulation of cell projection organization; IDA:RGD.
 GO:0051461; P:positive regulation of corticotropin secretion; IDA:RGD.
 GO:0045046; P:protein import into peroxisome membrane; IEA:Compara.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 

Pfam

 PF00071; Ras 

SMART

 SM00175; RAB 

PROSITE

 PS51419; RAB 

PRINTS

 PR00449; RASTRNSFRMNG.