UniProt Accession

 AB17A_HUMAN; Q96GS6; A8K0G8; D6W5Z9; Q6PJU2; Q8WUH9; Q9BWL0; Q9H7Q9 

Genbank Protein ID

 AK024419; AK074043; AK289533; AK090438; AK074548; CH471139; CH471139; CH471139; BC000158; BC009256; BC011667; BC020512; BC033749; BC035961; BC071644; BC071876; BC094816 

Genbank Nucleotide ID

 BAB15709.1; BAB84869.1; BAF82222.1; BAC03419.1; BAC11052.1; EAW69441.1; EAW69444.1; EAW69446.1; AAH00158.1; AAH09256.1; AAH11667.1; AAH20512.1; AAH33749.1; AAH35961.1; AAH71644.1; AAH71876.1; AAH94816.1 

Protein Name

 Alpha/beta hydrolase domain-containing protein 17A 

Protein Synonyms/Alias

  

Gene Name

 ABHD17A 

Gene Synonyms/Alias

 C19orf27; FAM108A1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
67	SGAPGRWKLHLTERA	ubiquitination	[1]
92	TIEVFPTKSARGNRV	ubiquitination	[2]
278	VAFPDTKKTYCFDAF	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

 ACT_SITE 190 190 Charge relay system (By similarity).
 ACT_SITE 255 255 Charge relay system (By similarity).
 ACT_SITE 284 284 Charge relay system (By similarity).
 MOD_RES 307 307 Phosphoserine.  

Keyword

 Alternative splicing; Complete proteome; Hydrolase; Phosphoprotein; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 310 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS