CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013723
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glycerol kinase 
Protein Synonyms/Alias
 ATP:glycerol 3-phosphotransferase; Glycerokinase; GK 
Gene Name
 glpK 
Gene Synonyms/Alias
 GK1360 
Created Date
 July 27, 2013 
Organism
 Geobacillus kaustophilus (strain HTA426) 
NCBI Taxa ID
 235909 
Lysine Modification
Position
Peptide
Type
References
282GEKAVASKHGLLTTIacetylation[1]
Reference
 [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus.
 Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG.
 Proteomics. 2013 Aug;13(15):2278-82. [PMID: 23696451] 
Functional Description
 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity). 
Sequence Annotation
 NP_BIND 410 414 ATP (By similarity).
 BINDING 12 12 Substrate (By similarity).
 BINDING 16 16 ATP (By similarity).
 BINDING 82 82 Substrate (By similarity).
 BINDING 134 134 Substrate (By similarity).
 BINDING 244 244 Substrate (By similarity).
 BINDING 266 266 ATP (By similarity).
 BINDING 309 309 ATP; via carbonyl oxygen (By similarity).  
Keyword
 ATP-binding; Complete proteome; Glycerol metabolism; Kinase; Nucleotide-binding; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 496 AA 
Protein Sequence
MNQYILAIDQ GTTSSRAILF NQKGEIVHMA QKEFTQYFPQ PGWVEHNANE IWGSVLAVIA 60
SVLSEAQVKP EQVAAIGITN QRETTVVWEK DTGNPIYNAI VWQSRQTAGI CDELKAKGYD 120
PLFREKTGLL IDAYFSGTKV KWILDHVEGA RERAERGELL FGTIDTWLIW KLSGGRAHVT 180
DYSNASRTLM FNIHTLEWDD ELLDILGVPK AMLPEVRPSS EVYAKTAPYH FFGVEVPIAG 240
AAGDQQAALF GQACFTEGMA KNTYGTGCFM LMNTGEKAVA SKHGLLTTIA WGIDGKVEYA 300
LEGSIFVAGS AIQWLRDGLR MIKTAADSEA YAEKVESTDG VYVVPAFVGL GTPYWDSEVR 360
GAVFGLTRGT TKEHFIRATL ESLAYQTKDV LAAMEADSGI SLTTLRVDGG AVKNNFLMQF 420
QSDLLAVPVE RPVVNETTAL GAAYLAGLAV GYWNSRDDIA AQWQLERRFE PKMDDDKRTM 480
LYDGWKKAVR AAMAFK 496 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0004370; F:glycerol kinase activity; IEA:HAMAP.
 GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
 GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:HAMAP. 
Interpro
 IPR018485; Carb_kinase_FGGY_C.
 IPR018483; Carb_kinase_FGGY_CS.
 IPR018484; Carb_kinase_FGGY_N.
 IPR005999; Glycerol_kin. 
Pfam
 PF02782; FGGY_C
 PF00370; FGGY_N 
SMART
  
PROSITE
 PS00933; FGGY_KINASES_1
 PS00445; FGGY_KINASES_2 
PRINTS