CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013644
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GTP-binding protein SAR1b 
Protein Synonyms/Alias
  
Gene Name
 Sar1b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
46TTLLHMLKDDRLGQHacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity). 
Sequence Annotation
 NP_BIND 32 39 GTP (By similarity).
 NP_BIND 75 78 GTP (By similarity).
 NP_BIND 134 137 GTP (By similarity).
 METAL 34 34 Magnesium (By similarity).
 METAL 75 75 Magnesium (By similarity).  
Keyword
 Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; GTP-binding; Magnesium; Membrane; Metal-binding; Nucleotide-binding; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 198 AA 
Protein Sequence
MSFIFDWIYS GFSSVLQFLG LYKKTGKLVF LGLDNAGKTT LLHMLKDDRL GQHVPTLHPT 60
SEELTIAGMT FTTFDLGGHL QARRVWKNYL PAINGIVFLV DCADHERLLE SKEELDSLMT 120
DETIANVPIL ILGNKIDRPE AISEERLREM FGLYGQTTGK GSVSLKELNA RPLEVFMCSV 180
LKRQGYGEGF RWMAQYID 198 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR006689; Small_GTPase_ARF/SAR.
 IPR006687; Small_GTPase_SAR1. 
Pfam
 PF00025; Arf 
SMART
 SM00178; SAR 
PROSITE
 PS51422; SAR1 
PRINTS
 PR00328; SAR1GTPBP.