UniProt Accession

 H0YNE3_HUMAN; H0YNE3 

Genbank Protein ID

 AL136295 

Genbank Nucleotide ID

  

Protein Name

 Proteasome activator complex subunit 1 

Protein Synonyms/Alias

  

Gene Name

 PSME1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
13	VQPEAQAKVDVFRED	acetylation	[1]
13	VQPEAQAKVDVFRED	ubiquitination	[1, 2]
24	FREDLCTKTENLLGS	ubiquitination	[1, 2]
35	LLGSYFPKKISELDA	acetylation	[1]
35	LLGSYFPKKISELDA	ubiquitination	[1, 2, 3]
36	LGSYFPKKISELDAF	ubiquitination	[1, 2]

Reference

 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 233 AA 

Protein Sequence

Gene Ontology

 GO:0008537; C:proteasome activator complex; IEA:InterPro. 

Interpro

 IPR003185; Proteasome_activ_REG_asu.
 IPR009077; Proteasome_activ_REG_asu/bsu.
 IPR003186; Proteasome_activ_REG_bsu. 

Pfam

 PF02251; PA28_alpha
 PF02252; PA28_beta 

SMART

  

PROSITE

  

PRINTS