| Tag | Content |
|---|
| CPLM ID | CPLM-016119 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Brain-specific angiogenesis inhibitor 3 |
Protein Synonyms/Alias | |
Gene Name | Bai3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 1385 | FEPRTAVKNFMASEL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma (By similarity). |
Sequence Annotation | DOMAIN 30 159 CUB.
DOMAIN 291 343 TSP type-1 1.
DOMAIN 345 398 TSP type-1 2.
DOMAIN 400 453 TSP type-1 3.
DOMAIN 455 508 TSP type-1 4.
DOMAIN 816 868 GPS.
MOD_RES 619 619 Phosphoserine (By similarity).
MOD_RES 1220 1220 Phosphoserine.
MOD_RES 1411 1411 Phosphoserine.
CARBOHYD 51 51 N-linked (GlcNAc...) (Potential).
CARBOHYD 54 54 N-linked (GlcNAc...) (Potential).
CARBOHYD 82 82 N-linked (GlcNAc...) (Potential).
CARBOHYD 105 105 N-linked (GlcNAc...) (Potential).
CARBOHYD 241 241 N-linked (GlcNAc...) (Potential).
CARBOHYD 337 337 N-linked (GlcNAc...) (Potential).
CARBOHYD 418 418 N-linked (GlcNAc...) (Potential).
CARBOHYD 540 540 N-linked (GlcNAc...) (Potential).
CARBOHYD 625 625 N-linked (GlcNAc...) (Potential).
CARBOHYD 779 779 N-linked (GlcNAc...) (Potential).
CARBOHYD 812 812 N-linked (GlcNAc...) (Potential).
CARBOHYD 828 828 N-linked (GlcNAc...) (Potential).
CARBOHYD 937 937 N-linked (GlcNAc...) (Potential).
DISULFID 303 336 By similarity.
DISULFID 307 342 By similarity.
DISULFID 318 326 By similarity.
DISULFID 357 392 By similarity.
DISULFID 361 397 By similarity.
DISULFID 372 382 By similarity.
DISULFID 412 447 By similarity.
DISULFID 416 452 By similarity.
DISULFID 427 437 By similarity.
DISULFID 467 502 By similarity.
DISULFID 471 507 By similarity.
DISULFID 482 492 By similarity.
DISULFID 514 549 By similarity.
DISULFID 537 567 By similarity.
DISULFID 819 851 By similarity.
DISULFID 839 853 By similarity. |
Keyword | Cell membrane; Complete proteome; Disulfide bond; G-protein coupled receptor; Glycoprotein; Membrane; Phosphoprotein; Receptor; Reference proteome; Repeat; Signal; Transducer; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1522 AA |
Protein Sequence | MKAVRNLLIY IFSTYLLVMF GFNAAQDFWC STLVKGVIYG SYSVSEMFPK NFTNCTWTLE 60
NPDPTKYSIY LKFSKKDLSC SNFSLLAYQF DHFSHEKIKD LLRKNHSIMQ LCSSKNAFVF 120
LQYDKNFIQI RRVFPTDFPG LQKKVEEDQK SFFEFLVLNK VSPSQFGCHV LCTWLESCLK 180
SENGRTESCG IMYTKCTCPQ HLGEWGIDDQ SLVLLNNVVL PLNEQTEGCL TQELQTTQVC 240
NLTREAKRPP KEEFGMMGDH TIKSQRPRSV HEKRVPQEQA DAAKFMAQTG ESGVEEWSQW 300
SACSVTCGQG SQVRTRTCVS PYGTHCSGPL RESRVCNNTA LCPVHGVWEE WSPWSLCSFT 360
CGRGQRTRTR SCTPPQYGGR PCEGPETHHK PCNIALCPVD GQWQEWSSWS HCSVTCSNGT 420
QQRSRQCTAA AHGGSECRGP WAESRECYNP ECTANGQWNQ WGHWSGCSKS CDGGWERRMR 480
TCQGAAVTGQ QCEGTGEEVR RCSEQRCPAP YEICPEDYLI SMVWKRTPAG DLAFNQCPLN 540
ATGTTSRRCS LSLHGVASWE QPSFARCISN EYRHLQHSIK EHLAKGQRML AGDGMSQVTK 600
TLLDLTQRKN FYAGDLLVSV EILRNVTDTF KRASYIPASD GVQNFFQIVS NLLDEENKEK 660
WEDAQQIYPG SIELMQVIED FIHIVGMGMM DFQNSYLMTG NVVASIQKLP AASVLTDINF 720
PMKGRKGMVD WARNSEDRVV IPKSIFTPVS SKELDESSVF VLGAVLYKNL DLILPTLRNY 780
TVVNSKVIVV TIRPEPKTTD SFLEIELAHL ANGTLNPYCV LWDDSKSNES LGTWSTQGCK 840
TVLTDASHTK CLCDRLSTFA ILAQQPREIV MESSGTPSVT LIVGSGLSCL ALITLAVVYA 900
ALWRYIRSER SIILINFCLS IISSNILILV GQTQTHNKSI CTTTTAFLHF FFLASFCWVL 960
TEAWQSYMAV TGKIRTRLIR KRFLCLGWGL PALVVATSVG FTRTKGYGTD HYCWLSLEGG 1020
LLYAFVGPAA AVVLVNMVIG ILVFNKLVSR DGILDKKLKH RAGQMSEPHS GLTLKCAKCG 1080
VVSTTALSAT TASNAMASLW SSCVVLPLLA LTWMSAVLAM TDKRSILFQI LFAVFDSLQG 1140
FVIVMVHCIL RREVQDAFRC RLRNCQDPIN ADSSSSFPNG HAQIMTDFEK DVDIACRSVL 1200
HKDIGPCRAA TITGTLSRIS LNDDEEEKGT NPEGLSYSTL PGNVISKVII QQPTGLHMPM 1260
SMNELSNPCL KKENTELRRT VYLCTDDNLR GADMDIVHPQ ERMMESDYIV MPRSSVSTQP 1320
SMKEESKMNI GMETLPHERL LHYKVNPEFN MNPPVMDQFN MNLDQHLAPQ EHMQNLPFEP 1380
RTAVKNFMAS ELDDNVGLSR SETGSTISMS SLERRKSRYS DLDFEKVMHT RKRHMELFQE 1440
LNQKFQTLDR FRDIPNTSSM ENPAPNKNPW DTFKPPSEYQ HYTTINVLDT EAKDTLELRP 1500
AEWEKCLNLP LDVQEGDFQT EV 1522 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW. GO:0016525; P:negative regulation of angiogenesis; IEA:InterPro. GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |