CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030492
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ90354 fis, clone NT2RP2003390, highly similar to Translocation protein SEC63 homolog 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
633ALLETKSKITHPVYSubiquitination[1]
688LKFPAPGKPGNYQYTubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Chaperone. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 760 AA 
Protein Sequence
MAGQQFQYDD SGNTFFYFLT SFVGLIVIPA TYYLWPRDQN AEQIRLKNIR EVYGRCMWYR 60
LRLLKPQPNI IPTVKKIVLL AGWALFLFLA YKVSKTDREY QEYNPYEVLN LDPGATVAEI 120
KKQYRLLSLK YHPDKGGDEV MFMRIAKAYA ALTDEESRKN WEEFGNPDGP QATSFGIALP 180
AWIVDQKNSI LVLLVYGLAF MVILPVVVGS WWYRSIRYSG DQILIRTTQI YTYFVYKTRN 240
MDMKRLIMVL AGASEFDPQY NKDATSRPTD NILIPQLIRE IGSINLKKNE PPLTCPYSLK 300
ARVLLLSHLA RMKIPETLEE DQQFMLKKCP ALLQEMVNVI CQLIVMARNR EEREFRAPTL 360
ASLENCMKLS QMAVQGLQQF KSPLLQLPHI EEDNLRRVSN HKKYEIKTIQ DLVSLKESDR 420
HTLLHFLEDE KYEEVMAVLG SFPYVTMDIK SQVLDDEDSN NITVGSLVTV LVKLTRQTMA 480
EVFEKEQSIC AAEEQPAEDG QGETNKNRTK GGWQQKSKGP KKTAKSKKKK PLKKKPTPVL 540
LPQSKQQKQK QANGVVGNEA AVKEDEEEVS DKGSDSEEEE TNRDSQSEKD DGSDRDSDRE 600
QDEKQNKDDE AEWQELQQSI QRKERALLET KSKITHPVYS LYFPEEKQEW WWLYIADRKE 660
QTLISMPYHV CTLKDTEEVE LKFPAPGKPG NYQYTVFLRS DSYMGLDQIK PLKLEVHEAK 720
PVPENHPQWD TAIEGDEDQE DSEGFEDSFE EEEEEEEDDD 760 
Gene Ontology
 GO:0008565; F:protein transporter activity; IEA:InterPro.
 GO:0031204; P:posttranslational protein targeting to membrane, translocation; IEA:InterPro. 
Interpro
 IPR001623; DnaJ_domain.
 IPR027137; Sec63.
 IPR004179; Sec63-dom. 
Pfam
 PF00226; DnaJ
 PF02889; Sec63 
SMART
 SM00271; DnaJ
 SM00611; SEC63
 SM00973; Sec63 
PROSITE
 PS50076; DNAJ_2 
PRINTS
 PR00625; JDOMAIN.