CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020650
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dehydrogenase/reductase SDR family member 7 
Protein Synonyms/Alias
 Retinal short-chain dehydrogenase/reductase 4; retSDR4 
Gene Name
 Dhrs7 
Gene Synonyms/Alias
 Retsdr4 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
101CLENGNLKEKDILVLubiquitination[1]
252AFTEEVTKSMRNNIDubiquitination[1]
331LDPDLPYKFLKAKKDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 NP_BIND 54 78 NAD (By similarity).
 ACT_SITE 203 203 Proton acceptor (By similarity).
 BINDING 190 190 Substrate (By similarity).  
Keyword
 Complete proteome; NAD; Oxidoreductase; Reference proteome; Signal. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 338 AA 
Protein Sequence
MSWELLLWLL ALCALILPLV QLLRFLRADA DLTLLWAEWQ GRRPEWELTD MVVWVTGASS 60
GIGEELAFQL SKLGVSLVLS ARRAQELERV KRRCLENGNL KEKDILVLPL DLTDTSSHEA 120
ATKAVLQEFG KIDILVNNGG RSQRSLVLET NLDVFKELIN LNYIGTVSLT KCVLPHMIER 180
KQGKIVTVNS IAGIASVSLS SGYCASKHAL RGFFNALHSE LGQYPGITFC NVYPGPVQSD 240
IVKNAFTEEV TKSMRNNIDQ SYKMPTSRCV RLMLISMAND LKEVWISDHP VLLGAYIWQY 300
MPTWAAWLNC KLGKERIQNF KNNLDPDLPY KFLKAKKD 338 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. 
Interpro
 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS. 
Pfam
 PF00106; adh_short 
SMART
  
PROSITE
 PS00061; ADH_SHORT 
PRINTS
 PR00081; GDHRDH.
 PR00080; SDRFAMILY.