| Tag | Content |
|---|
| CPLM ID | CPLM-007939 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Rap1 GTPase-activating protein 1 |
Protein Synonyms/Alias | Rap1GAP; Rap1GAP1 |
Gene Name | RAP1GAP |
Gene Synonyms/Alias | KIAA0474; RAP1GA1 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 268 | KVKLQDFKGFRGGLD | ubiquitination | [1] | | 387 | PDPAVFRKGPEFQEF | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. |
Sequence Annotation | DOMAIN 1 17 GoLoco.
DOMAIN 181 397 Rap-GAP.
MOD_RES 484 484 Phosphoserine.
MOD_RES 499 499 Phosphoserine. |
Keyword | 3D-structure; Alternative splicing; Complete proteome; Golgi apparatus; GTPase activation; Membrane; Phosphoprotein; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 663 AA |
Protein Sequence | MAQLRPAVPP GRPRRGSLPA GASWQNTDLF EMIEKMQGSR MDEQRCSFPP PLKTEEDYIP 60
YPSVHEVLGR EGPFPLILLP QFGGYWIEGT NHEITSIPET EPLQSPTTKV KLECNPTARI 120
YRKHFLGKEH FNYYSLDAAL GHLVFSLKYD VIGDQEHLRL LLRTKCRTYH DVIPISCLTE 180
FPNVVQMAKL VCEDVNVDRF YPVLYPKASR LIVTFDEHVI SNNFKFGVIY QKLGQTSEEE 240
LFSTNEESPA FVEFLEFLGQ KVKLQDFKGF RGGLDVTHGQ TGTESVYCNF RNKEIMFHVS 300
TKLPYTEGDA QLQRKRHIGN DIVAVVFQDE NTPFVPDMIA SNFLHAYVVV QAEGGGPDGP 360
LYKVSVTARD DVPFFGPPLP DPAVFRKGPE FQEFLLTKLI NAEYACYKAE KFAKLEERTR 420
AALLETLYEE LHIHSQSMMG LGGDEDKMEN GSGGGGFFES FKRVIRSRSQ SMDAMGLSNK 480
KPNTVSTSHS GSFAPNNPDL AKAAGISLIV PGKSPTRKKS GPFGSRRSSA IGIENIQEVQ 540
EKRESPPAGQ KTPDSGHVSQ EPKSENSSTQ SSPEMPTTKN RAETAAQRAE ALKDFSRSSS 600
SASSFASVVE ETEGVDGEDT GLESVSSSGT PHKRDSFIYS TWLEDSVSTT SGGSSPGPSR 660
SPHPDAGKLG DPACPEIKIQ LEASEQHMPQ LGC 693 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |