UniProt Accession

 E9PJF1_HUMAN; E9PJF1 

Genbank Protein ID

 AL023693 

Genbank Nucleotide ID

  

Protein Name

 Transcriptional activator Myb 

Protein Synonyms/Alias

  

Gene Name

 MYB 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
442	FHRDQTVKTQKENTV	ubiquitination	[1]
445	DQTVKTQKENTVFRT	acetylation	[2]
445	DQTVKTQKENTVFRT	ubiquitination	[1, 3]
471	PRTPTPFKHALAAQE	acetylation	[2]
471	PRTPTPFKHALAAQE	ubiquitination	[1, 2, 3]
480	ALAAQEIKYGPLKML	ubiquitination	[1, 2, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 581 AA 

Protein Sequence

Gene Ontology

 GO:0003682; F:chromatin binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 

Interpro

 IPR015395; C-myb_C.
 IPR009057; Homeodomain-like.
 IPR017930; Myb_dom.
 IPR001005; SANT/Myb.
 IPR012642; Tscrpt_reg_Wos2-domain. 

Pfam

 PF09316; Cmyb_C
 PF07988; LMSTEN
 PF00249; Myb_DNA-binding 

SMART

 SM00717; SANT 

PROSITE

 PS51294; HTH_MYB 

PRINTS